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AB1565 Anti-Vasopressin Antibody

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AB1565
100 µL  
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      Replacement Information

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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, Rb, ShICC, IH(P), RIA, WBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB1565
      ReplacesAB937
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Vasopressin Antibody
      References
      Product Information
      FormatSerum
      HS Code3002 15 90
      Control
      • Hypothalamus
      PresentationNeat rabbit antisera. Liquid, with 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Vasopressin Antibody detects level of Vasopressin & has been published & validated for use in IC, IH(P), RIA & WB.
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry (Paraffin)
      • Radioimmunoassay
      • Western Blotting
      Application NotesImmunohistochemistry: 1:5,000-1:10,000 (18-24 hour incubation) on formalin, Bouin's or Zamboni's fixed tissue. Will react on paraffin embedded tissue.

      Immunocytochemistry: 1:1,000-1:200,000 (18-24 hour incubation) on fetal rat neurons.

      Immunoblotting: 1:1,000

      RIA: 1:30,000-1:750,000. Sensitivity of < 1 pg/mL.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenArginine vasopressin (Sigma) conjugated to thyroglobulin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Vasopressin. Less than 1% cross-reactivity with oxytocin.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Rabbit
      • Sheep
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin II and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin II, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI).
      Gene Symbol
      • AVP
      • AVP-NPII
      • VP
      • AVRP
      • ARVP
      • ADH
      Purification MethodUnpurified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01185 # Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.
      SIZE: 164 amino acids; 17325 Da
      SUBCELLULAR LOCATION: Secreted.
      DISEASE: SwissProt: P01185 # Defects in AVP are the cause of autosomal dominant neurohypophyseal diabetes insipidus (ADNDI) [MIM:125700]. ADNDI is characterized by persistent thirst, polydipsia and polyuria. The disease is transmitted in an autosomal dominant mode and appears to be largely if not completely penetrant. & Defects in AVP are the cause of autosomal recessive neurohypophyseal diabetes insipidus (ARNDI) [MIM:125700]. ARNDI is characterized by persistent thirst, polydipsia and polyuria. Most mutations are hypothesized to trigger neurodegeneration via disruption of preproAVP-NPII processing.
      SIMILARITY: SwissProt: P01185 ## Belongs to the vasopressin/oxytocin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      AB1565 04053252671647

      Documentation

      Anti-Vasopressin Antibody MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Anti-Vasopressin Antibody Certificati d'Analisi

      TitoloNumero di lotto
      RABBIT ANTI-VASOPRESSIN 2477836
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY - 2118000 2118000
      RABBIT ANTI-VASOPRESSIN POLYCLONAL ANTIBODY - 2428472 2428472
      RABBIT ANTI-VASOPRESSIN - 3380350 3380350
      RABBIT ANTI-VASOPRESSIN - 3611857 3611857
      RABBIT ANTI-VASOPRESSIN - 3739735 3739735
      RABBIT ANTI-VASOPRESSIN - 3906989 3906989
      RABBIT ANTI-VASOPRESSIN - 4043821 4043821
      RABBIT ANTI-VASOPRESSIN - 4204601 4204601
      RABBIT ANTI-VASOPRESSIN -2607294 2607294

      Riferimenti bibliografici

      Panoramica dei riferimenti bibliograficiCodice d'identificazione nel Pub Med
      An ultrastructural analysis of the effects of ethanol self-administration on the hypothalamic paraventricular nucleus in rhesus macaques.
      Jimenez, VA; Helms, CM; Cornea, A; Meshul, CK; Grant, KA
      Frontiers in cellular neuroscience  9  260  2015

      Mostra il sommario
      26236193 26236193
      Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease.
      Lim, AS; Ellison, BA; Wang, JL; Yu, L; Schneider, JA; Buchman, AS; Bennett, DA; Saper, CB
      Brain : a journal of neurology  137  2847-61  2014

      Mostra il sommario
      25142380 25142380
      Syndrome of inappropriate antidiuretic hormone secretion in patients with olfactory neuroblastoma.
      Stacey T Gray,Eric H Holbrook,Mohammed H Najm,Peter M Sadow,William T Curry,Derrick T Lin
      Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery  147  2011

      Mostra il sommario
      22368044 22368044
      Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction.
      Mark J McCabe,Carles Gaston-Massuet,Vaitsa Tziaferi,Louise C Gregory,Kyriaki S Alatzoglou,Massimo Signore,Eduardo Puelles,Dianne Gerrelli,I Sadaf Farooqi,Jamal Raza,Joanna Walker,Scott I Kavanaugh,Pei-San Tsai,Nelly Pitteloud,Juan-Pedro Martinez-Barbera,Mehul T Dattani
      The Journal of clinical endocrinology and metabolism  96  2010

      Mostra il sommario
      21832120 21832120
      Early life stress disrupts peripubertal development of aggression in male mice.
      Tsuda MC, Yamaguchi N, Ogawa S
      Neuroreport  22  259-63.  2010

      Mostra il sommario
      21403582 21403582
      Functional hypothalamic amenorrhea due to increased CRH tone in melanocortin receptor 2-deficient mice.
      Matsuwaki, T; Nishihara, M; Sato, T; Yoda, T; Iwakura, Y; Chida, D
      Endocrinology  151  5489-96  2009

      Mostra il sommario
      20881239 20881239
      Different antipsychotics elicit different effects on magnocellular oxytocinergic and vasopressinergic neurons as revealed by Fos immunohistochemistry.
      A Kiss, J Bundzikova, Z Pirnik, JD Mikkelsen
      Journal of neuroscience research  88  677-85  2009

      Mostra il sommario
      19774673 19774673
      Vasopressin synthesis by the magnocellular neurons is different in the supraoptic nucleus and in the paraventricular nucleus in human and experimental septic shock.
      Sonneville R, Guidoux C, Barrett L, Viltart O, Mattot V, Polito A, Siami S, de la Grandmaison GL, Blanchard A, Singer M, Annane D, Gray F, Brouland JP, Sharshar T
      Brain Pathol  20  613-22. Epub 2009 Nov 9.  2009

      Mostra il sommario
      20015289 20015289
      A role of the LIM-homeobox gene Lhx2 in the regulation of pituitary development.
      Zhao Y, Mailloux CM, Hermesz E, Palkóvits M, Westphal H
      Developmental biology  337  313-23  2009

      Mostra il sommario Testo completo dell'articolo
      19900438 19900438
      Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction.
      Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Furukawa Y, Yamada M, Nukina N
      Human molecular genetics  2009

      Mostra il sommario
      20185558 20185558

      Scheda tecnica

      Titolo
      Anti-Vasopressin - Data Sheet