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AB9303 Anti-Trace Amine Receptor 1 Antibody

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AB9303
50 µg  
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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, Mk, RIH(P), WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9303
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Trace Amine Receptor 1 Antibody
      Alternate Names
      • TA1
      • TAAR1
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Trace Amine Receptor 1 Antibody detects level of Trace Amine Receptor 1 & has been published & validated for use in IH(P) & WB.
      Key Applications
      • Immunohistochemistry (Paraffin)
      • Western Blotting
      Application NotesImmunohistochemistry on paraffin embedded tissue sections.

      Western blot.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the 3rd cytoplasmic domain of human Trace Amine Receptor 1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Trace Amine Receptor 1 [TAAR1, TA1].
      Species Reactivity
      • Human
      • Monkey
      • Rat
      Species Reactivity NoteThe immunogen has 63% similarity with mouse.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryTAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM]
      Gene Symbol
      • TAAR1
      • TA1
      • TRAR1
      • TaR-1
      • MGC138399
      • RP11-295F4.9
      • MGC126874
      • TAR1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q96RJ0 # Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
      SIZE: 339 amino acids; 39092 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestin. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle, and spleen.
      SIMILARITY: SwissProt: Q96RJ0 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      AB9303 04053252363078

      Documentation

      Anti-Trace Amine Receptor 1 Antibody MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Anti-Trace Amine Receptor 1 Antibody Certificati d'Analisi

      TitoloNumero di lotto
      RABBIT ANTI- TRACE AMINE RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3063365
      RABBIT ANTI- TRACE AMINE RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2003015 2003015
      RABBIT ANTI- TRACE AMINE RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2005934 2005934
      RABBIT ANTI- TRACE AMINE RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2080852 2080852
      RABBIT ANTI- TRACE AMINE RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2361853 2361853