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MABC292 Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD

This Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD is validated for use in Western Blotting for the detection of TAOK1 (long isoform).

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: TAOK1, KIAA1361, MAP3K16, MARKK UniProt Number: Q7L7X3
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MABC292
100 µg  
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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC292
      DescriptionAnti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD
      Alternate Names
      • Serine/threonine-protein kinase TAO1
      • Kinase from chicken homolog B
      • hKFC-B
      • MARK Kinase
      • MARKK
      • Prostate-derived sterile 20-like kinase 2
      • PSK-2
      • PSK2
      • Prostate-derived STE20-like kinase 2
      • Thousand and one amino acid protein kinase 1
      • TAOK1
      • hTAOK1
      Background InformationTAOK1 , also known as Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2/PSK2, Prostate-derived STE20-like kinase 2, or Thousand and one amino acid protein kinase 1, TAOK1/hTAOK1, and encoded by the gene TAOK1/KIAA1361/MAP3K16/MARKK, is an important serine/threonine protein kinase involved in a variety of processes including p38/MAPK14 stress responses, DNA damage responses and cytoskeleton stability. TAOK1 also acts as regulator of apoptosis and controls the morphological changes associated with apoptosis including cell contraction, membrane blebbing and apoptotic body formation. TAOK1 is expressed in many tissues but highly expressed in testis as well as brain, colon and muscle. TAOK1 is localized to the cytoplasm and a target for caspase-3 as well as SPRED1 a regulator of the MAP kinase cascade.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD is validated for use in Western Blotting for the detection of TAOK1 (long isoform).
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting Analysis: A representative lot detected TAOK1 in HeLa cell lysate, but not in TAOK1 siRNA transfected HeLa cell lysate (Prof. Viji Draviam, University of Cambridge).
      Biological Information
      ImmunogenLinear peptide corresponding to the C-terminus of human TAOK1.
      EpitopeC-terminus
      Clone1.2
      Concentration1 mg/mL
      HostMouse
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TAOK1
      • KIAA1361
      • MAP3K16
      • MARKK
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~116 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected TAOK1 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      MABC292 04053252978753

      Documentation

      Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD Certificati d'Analisi

      TitoloNumero di lotto
      Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - Q2436816 Q2436816
      Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - 3291369 3291369
      Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - 3756183 3756183
      Anti-TAOK1 (long isoform), clone TAO1_1.2_VMD - 4175801 4175801

      Riferimenti bibliografici

      Panoramica dei riferimenti bibliograficiCodice d'identificazione nel Pub Med
      TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.
      Shrestha, Roshan L, et al.
      Open Biol, 4: (2014)  2014

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