Millipore Sigma Vibrant Logo

MABN130 Anti-SQSTM1 Antibody, clone 20F1.1

Anti-SQSTM1 Antibody, clone 20F1.1 is a highly specific mouse monoclonal antibody, that targets p62 & has been tested in western blotting & IHC.

Anti-SQSTM1 Antibody, clone 20F1.1: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: SQSTM1, ORCA, OSIL UniProt Number: Q13501
View Products on Sigmaaldrich.com
MABN130
100 µg  
Ricerca del prezzo in corso...
Non è stato possibile trovare il prezzo
La quantità minima deve essere un multiplo di
Maximum Quantity is
Al termine dell'ordine Maggiori informazioni
Lei ha salvato ()
 
—
Richiedi il prezzo
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      Offerte speciali

       

      Contatti il Servizio Clienti

      Panoramica

      Replacement Information

      Offerte speciali

      100% Performance Guaranteed

      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN130
      DescriptionAnti-SQSTM1 Antibody, clone 20F1.1
      Alternate Names
      • Sequestosome-1
      • EBI3-associated protein of 60 kDa
      • EBIAP
      • p60
      • Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
      • Ubiquitin-binding protein p62
      Background InformationUbiquitin-binding protein p62, also known as Sequestosome-1 (SQSTM1), is a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals. Defects in p62/SQSTM1 are a cause of Paget disease of bone (PDB), a metabolic bone disease affecting the axial skeleton and characterized by focal areas of increased and disorganized bone turn-over due to activated osteoclasts
      References
      Product Information
      FormatPurified
      Control
      • Rat brain tissue lysate
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-SQSTM1 Antibody, clone 20F1.1 is a highly specific mouse monoclonal antibody, that targets p62 & has been tested in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SQSTM1 in human thalamus and human cerebellum tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human SQSTM1.
      Clone20F1.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Rat
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SQSTM1
      • ORCA
      • OSIL
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~60 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected SQSTM1 in 10 µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      MABN130 04053252908729

      Prodotti e applicazioni correlate

      Related Products

      Numero di catalogo Descrizione  
      MABC32 Anti-p62 (Sequestosome-1) Antibody, clone 11C9.2 Prezzi e disponibilità

      Categorie

      Life Science Research > Antibodies and Assays > Primary Antibodies