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06-1041 Anti-RIG-I, CT Antibody

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06-1041
100 µg  
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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number06-1041
      DescriptionAnti-RIG-I, CT Antibody
      Alternate Names
      • Probable ATP-dependent RNA helicase DDX58
      • DEAD box protein 58
      • Retinoic acid-inducible gene 1 protein
      • RIG-1
      • Retinoic acid-inducible gene I protein
      • RIG-I
      Background InformationRetinoic acid-inducible gene 1 (RIG-1, DDX58) is a cytoplasmic protein belonging to the family of RIG-1-like receptor (RLR) family. It is a multidomain protein containing an N-terminal caspase recruitment domain (CARD); a DExD/H box helicase domain; and a C-terminal repression domain. RIG-1 has a well-documented role in innate immunity, as a virus-sensing protein that detects viral RNA molecules and induces the production of IFN-β through activation of the inflammasome complex.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours.
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-RIG-I, C-terminus Antibody is an antibody against RIG-I, C-terminus for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human RIG-I.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of RIG-I.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DDX58
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~102 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for 12 hours.

      Western Blot Analysis: 1 µg/mL of this antibody detected RIG-I in 10 µg of untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours..
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      06-1041 04053252440236

      Documentation

      Anti-RIG-I, CT Antibody MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Anti-RIG-I, CT Antibody Certificati d'Analisi

      TitoloNumero di lotto
      Anti-RIG-I, C-terminus - 3238050 3238050
      Anti-RIG-I, C-terminus - 3384864 3384864
      Anti-RIG-I, C-terminus - Q2009198 Q2009198
      Anti-RIG-I, C-terminus -2578590 2578590
      Anti-RIG-I, C-terminus -2591894 2591894
      Anti-RIG-I, C-terminus -2603856 2603856
      Anti-RIG-I, C-terminus -2624230 2624230
      Anti-RIG-I, C-terminus -2660182 2660182
      Anti-RIG-I, C-terminus -2700255 2700255
      Anti-RIG-I, C-terminus -2756674 2756674

      Brochure

      Titolo
      New Products: Volume 3, 2012

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      Categorie

      Life Science Research > Antibodies and Assays > Primary Antibodies