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AB3570P Anti-Organic Anion Transporting Polypeptide 1 Antibody

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AB3570P
50 µg  
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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RELISA, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB3570P
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Organic Anion Transporting Polypeptide 1 Antibody
      Alternate Names
      • oatp1
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Organic Anion Transporting Polypeptide 1 Antibody is validated for use in ELISA, WB for the detection of Organic Anion Transporting Polypeptide 1.
      Key Applications
      • ELISA
      • Western Blotting
      Application NotesWestern blot: 1-10 μg/mL using ECL.



      ELISA: 0.5-1 μg/mL using 1 μg/mL immunogen per well.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenA 17 amino acid peptide sequence near amino acid 285 of rat OATP1 (Jacquemin et al. 1994; Kullak-Ublick et al. 1995).
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes rat Organic Ion Transporter Polypetide 1 (OATP1). The immunogen shows no significant sequence homology with other OATs or other proteins

      SPECIES REACTIVITIES: The immunogen sequence is unique to rat. Reactivity with other species has not been confirmed.
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SLCO4A1
      • OATP1
      • POAT
      • OATPE
      • OATPRP1
      • OATP-RP1
      • SLC21A12
      • OATP4A1
      • OATP-E
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q96BD0 # Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate.
      SIZE: 722 amino acids; 77193 Da
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Ubiquitous, with the exception of spleen and leukocytes.
      SIMILARITY: SwissProt: Q96BD0 ## Belongs to the organo anion transporter (TC 2.A.60) family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

      During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      AB3570P 04053252476440

      Documentation

      Anti-Organic Anion Transporting Polypeptide 1 Antibody MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Anti-Organic Anion Transporting Polypeptide 1 Antibody Certificati d'Analisi

      TitoloNumero di lotto
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) - 3266812 3266812
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) - 3266816 3266816
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) -2537165 2537165
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) -2588509 2588509
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) -2654614 2654614
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) -2673763 2673763
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1) AFFINITY PURIFIED POLYCLONAL ANTIBODY 3060082

      Riferimenti bibliografici

      Panoramica dei riferimenti bibliograficiApplicazioneCodice d'identificazione nel Pub Med
      An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown.
      Yang, K; Pfeifer, ND; Hardwick, RN; Yue, W; Stewart, PW; Brouwer, KL
      Molecular pharmaceutics  11  766-75  2014

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      Western Blotting24410402 24410402
      Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver.
      Kullak-Ublick, G A, et al.
      Gastroenterology, 109: 1274-82 (1995)  1994

      Mostra il sommario
      7557095 7557095
      Expression cloning of a rat liver Na(+)-independent organic anion transporter.
      Jacquemin, E, et al.
      Proc. Natl. Acad. Sci. U.S.A., 91: 133-7 (1994)  1993

      Mostra il sommario
      8278353 8278353

      Scheda tecnica

      Titolo
      RABBIT ANTI-ORGANIC ANION TRANSPORTING POLYPEPTIDE 1 (OATP1)