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ABS12 Anti-Dia 1 Antibody

ABS12
100 µg  
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      Tabella delle specifiche principali

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS12
      DescriptionAnti-Dia 1 Antibody
      Alternate Names
      • Diaphanous homolog 1
      • Diaphanous-related formin-1
      • Protein diaphanous homolog 1
      • DFNA1
      • DIAP1
      • DIAPH1
      • DRF1
      • hDIA1
      • LFHL1
      Background InformationProtein diaphanous homolog 1, also known as Diaphanous-related formin-1 or DRF1, and encoded by the gene name DIAPH1 or DIAP1, is a homolog of Drosophila diaphanous, and it has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. DIAP1 has therefore been speculated to have a role in the regulation of actin polymerization in hair cells of the inner ear.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Dia 1 Antibody is an antibody against Dia 1 for use in Western Blotting and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: 2 µg/mL from a representative lot detected Dia 1 in HeLa, A431, and NIH/3T3 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the FH2 domain of human Dia 1.
      EpitopeFH2 Domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DIAPH1
      • DIAP1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~160 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: 0.2 µg/mL of this antibody detected Dia 1 in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      ABS12 04055977136241