182706 Sigma-AldrichAhR Antagonist II, SR1 - CAS 1227633-49-10 - Calbiochem
The AhR Antagonist II, SR1 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The AhR Antagonist II, SR1 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Sinonimi: 4-(2-(2-(Benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol, 4-[2-[[2-Benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]phenol, StemRegenin 1
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Panoramica
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Prezzi e disponibilità
| Numero di catalogo | Disponibilità | Confezionamento | Qtà/conf | Prezzo | Quantità | |
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| 182706-5MG |
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Bottiglia di vetro | 5 mg |
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| Description | |
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| Overview | A cell-permeable purine compound that acts as a high affinity AhR antagonist (IC50 = 127 nM against 3 nM TCDD-induced luciferase reporter activity in HepG2 cultures), but not a panel of 61 kinases. AhR expression and function knockouts by shRNAs, CH-223191 (Cat. No. 182705), or SR1 treatment all result in enhanced and sustained CD34+ population in long-term proliferating/expanding cultures of cord blood-derived HSCs (hematopoietic setem cells) in serum-free media containing Tpo (Cat. No. 605218), SCF (Cat. No. 569600), Flt3 Ligand (Cat. No. 343010), and IL-6 (Cat. No. 407652) in a reversible manner. SR1 is reactive toward human, monkey, and canine, but not rat or murine, species. |
| Catalogue Number | 182706 |
| Brand Family | Calbiochem® |
| Synonyms | 4-(2-(2-(Benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol, 4-[2-[[2-Benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]phenol, StemRegenin 1 |
| References | |
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| References | Boitano, A.E., et al. 2010. Science 329, 1345. |
| Product Information | |
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| CAS number | 1227633-49-9 |
| Form | White solid |
| Hill Formula | C₂₄H₂₃N₅OS |
| Chemical formula | C₂₄H₂₃N₅OS |
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| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥98% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Numero di catalogo | GTIN |
| 182706-5MG | 04055977204469 |
Documentation
AhR Antagonist II, SR1 - CAS 1227633-49-10 - Calbiochem MSDS
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AhR Antagonist II, SR1 - CAS 1227633-49-10 - Calbiochem Certificati d'Analisi
| Titolo | Numero di lotto |
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| 182706 |
Riferimenti bibliografici
| Panoramica delle referenze |
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| Boitano, A.E., et al. 2010. Science 329, 1345. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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