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441251 α₂-Macroglobulin, Human Plasma - Calbiochem

A multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a "trap" around most proteases.

α₂-Macroglobulin, Human Plasma - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: α₂M, α₂MG

Primary Target: broad range protease
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441251
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441251-10MG
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      441251-1MG
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          		 Fiala di plastica 1 mg
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          Description
          OverviewA multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a "trap" around most proteases. α2M is so large a molecule that it tends to remain intravascular. Localized on the surface of peripheral blood lymphocytes. Multifunctional activities include promoting growth of mammalian cells in culture, stimulating regeneration of lymphocytes in irradiated mice, transporting zinc, and acting as proteinase inhibitor that controls the clotting and fibrinolytic system.
          Catalogue Number441251
          Brand Family Calbiochem®
          Synonymsα₂M, α₂MG
          References
          ReferencesBonner, J.C., et al. 1995. J. Biol. Chem. 270, 16236.
          Lysiak, J.J., et al. 1995. J. Biol. Chem. 270, 21919.
          Boisset, N., et al. 1992. J. Struct. Biol. 108, 221.
          Barrett, A.J. 1980. Methods Enzymol. 80, 737.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          FormulationLyophilized from 30 mM sodium phosphate buffer, with glycine, pH 7.0.
          ReversibleN
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Targetbroad range protease
          Purity≥95% by SDS-PAGE
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Numero di catalogo GTIN
          441251-10MG 04055977206005
          441251-1MG 04055977205992

          Documentation

          α₂-Macroglobulin, Human Plasma - Calbiochem MSDS

          Titolo

          Scheda di sicurezza (MSDS) 

          α₂-Macroglobulin, Human Plasma - Calbiochem Certificati d'Analisi

          TitoloNumero di lotto
          441251

          Riferimenti bibliografici

          Panoramica delle referenze
          Bonner, J.C., et al. 1995. J. Biol. Chem. 270, 16236.
          Lysiak, J.J., et al. 1995. J. Biol. Chem. 270, 21919.
          Boisset, N., et al. 1992. J. Struct. Biol. 108, 221.
          Barrett, A.J. 1980. Methods Enzymol. 80, 737.
          Scheda tecnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-August-2008 RFH
          Synonymsα₂M, α₂MG
          DescriptionA multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a "trap" around most proteases. α2M is so large a molecule that it tends to remain intravascular. Localized on the surface of peripheral blood lymphocytes. Multifunctional activities include promoting growth of mammalian cells in culture, stimulating regeneration of lymphocytes in irradiated mice, transporting zinc, and acting as proteinase inhibitor that controls the clotting and fibrinolytic system.
          FormLyophilized
          FormulationLyophilized from 30 mM sodium phosphate buffer, with glycine, pH 7.0.
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Purity≥95% by SDS-PAGE
          SolubilityAqueous buffers
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBonner, J.C., et al. 1995. J. Biol. Chem. 270, 16236.
          Lysiak, J.J., et al. 1995. J. Biol. Chem. 270, 21919.
          Boisset, N., et al. 1992. J. Struct. Biol. 108, 221.
          Barrett, A.J. 1980. Methods Enzymol. 80, 737.