616520 Sigma-AldrichTRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<Synonymes: 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734
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Tableau de caractéristiques principal
CAS # | Empirical Formula |
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946387-07-1 | C₁₄H₂₂Cl₂N2O₂S |
Prix & Disponibilité
Référence | Disponibilité | Conditionnement | Qté | Prix | Quantité | |
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616520-10MG |
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Flacon en verre | 10 mg |
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Description | |
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Overview | A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM). |
Catalogue Number | 616520 |
Brand Family | Calbiochem® |
Synonyms | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734 |
References | |
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References | Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490. |
Product Information | |
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CAS number | 946387-07-1 |
Form | Yellow solid |
Hill Formula | C₁₄H₂₂Cl₂N2O₂S |
Chemical formula | C₁₄H₂₂Cl₂N2O₂S |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Purity | ≥95% by HPLC |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Référence | GTIN |
616520-10MG | 04055977185249 |