573102 Sigma-AldrichSTAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
More>> STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription. Less<<Synonymes: 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859
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Aperçu
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Tableau de caractéristiques principal
CAS # | Empirical Formula |
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501919-59-1 | C₁₆H₁₅NO₇S |
Prix & Disponibilité
Référence | Disponibilité | Conditionnement | Qté | Prix | Quantité | |
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573102-10MG |
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Ampoule plast. | 10 mg |
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573102-25MG |
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Ampoule plast. | 25 mg |
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Description | |
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Overview | A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). Also available as a 50 mM solution in DMSO (Cat. No. 573130). |
Catalogue Number | 573102 |
Brand Family | Calbiochem® |
Synonyms | 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859 |
References | |
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References | Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
Product Information | |
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CAS number | 501919-59-1 |
Form | Light beige solid |
Hill Formula | C₁₆H₁₅NO₇S |
Chemical formula | C₁₆H₁₅NO₇S |
Structure formula Image | |
Quality Level | MQ100 |
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Biological Information | |
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Purity | ≥95% by HPLC |
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Packaged under inert gas | Packaged under inert gas |
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Specifications |
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Global Trade Item Number | |
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Référence | GTIN |
573102-10MG | 04055977266429 |
573102-25MG | 04055977266436 |
Documentation
STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem FDS
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STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem Certificats d'analyse
Titre | Numéro de lot |
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573102 |
Références bibliographiques
Aperçu de la référence bibliographique |
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Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
Informations techniques
Titre |
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JAK/STAT Signaling Research Focus |