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476475 PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated - Calbiochem

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated

Primary Target: PKC
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476475
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₆₀H₁₁₇N₂₁O₁₁

Prix & Disponibilité

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476475-500UG
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      		 Ampoule plast. 500 μg
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      Description
      OverviewEpidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC50 = 5 µM).
      Catalogue Number476475
      Brand Family Calbiochem®
      SynonymsMyr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
      References
      ReferencesWard, N.E., and O’Brian, C.A. 1993. Biochemistry 32, 11903.
      O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
      Product Information
      ATP CompetitiveN
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₆₀H₁₁₇N₂₁O₁₁
      Chemical formulaC₆₀H₁₁₇N₂₁O₁₁
      Hygroscopic Hygroscopic
      ReversibleY
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKC
      Primary Target IC<sub>50</sub>5 µM against protein kinase C
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide ContentY
      Peptide SequenceMyr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      476475-500UG 04055977183818

      Documentation

      PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      476475

      Références bibliographiques

      Aperçu de la référence bibliographique
      Ward, N.E., and O’Brian, C.A. 1993. Biochemistry 32, 11903.
      O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-January-2010 RFH
      SynonymsMyr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
      DescriptionEpidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC50 = 5 µM) in intact cells.
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₆₀H₁₁₇N₂₁O₁₁
      Peptide SequenceMyr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
      Purity≥97% by HPLC
      SolubilityH₂O (5 mg/ml)
      Storage Protect from moisture
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Standard Handling
      ReferencesWard, N.E., and O’Brian, C.A. 1993. Biochemistry 32, 11903.
      O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.