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508225 InSolution™ Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem

A 10 mM (2 mg/516 µL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: (Z)-4-(1-(4-(Dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, (Z)-4-Hydroxytamoxifen, (Z)-4-OH-TAM, trans-4-Hydroxytamoxifen

Primary Target: Estrogen receptor
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508225
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Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
68047-06-3C₂₆H₂₉NO₂

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      Description
      Catalogue Number508225
      Brand Family Calbiochem®
      Synonyms(Z)-4-(1-(4-(Dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, (Z)-4-Hydroxytamoxifen, (Z)-4-OH-TAM, trans-4-Hydroxytamoxifen
      References
      ReferencesGundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.
      Product Information
      CAS number68047-06-3
      FormLiquid
      FormulationA 10 mM (2 mg/516 µL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen (Cat. No. 579002) in EtOH.
      Hill FormulaC₂₆H₂₉NO₂
      Chemical formulaC₂₆H₂₉NO₂
      Hygroscopic Hygroscopic
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetEstrogen receptor
      Purity≥99% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 11

      Highly flammable.
      S PhraseS: 16-7

      Keep away from sources of ignition - No Smoking.
      Keep container tightly closed.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Use only anhydrous, 200 proof ethanol for further dilutions.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      5082250001 04055977261769

      Documentation

      InSolution™ Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Gundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-January-2014 JSW
      Synonyms(Z)-4-(1-(4-(Dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, (Z)-4-Hydroxytamoxifen, (Z)-4-OH-TAM, trans-4-Hydroxytamoxifen
      DescriptionA cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.
      FormLiquid
      FormulationA 10 mM (2 mg/516 µL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen (Cat. No. 579002) in EtOH.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number68047-06-3
      Chemical formulaC₂₆H₂₉NO₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Use only anhydrous, 200 proof ethanol for further dilutions.
      Toxicity Harmful & Carcinogenic / Teratogenic
      ReferencesGundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.