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239785 Cyclophosphamide Monohydrate - CAS 6055-19-2 - Calbiochem

A widely used anti-neoplastic agent that also displays immunosuppressant properties.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA

Primary Target: Fas/Fas ligand pathway
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239785
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
6055-19-2C₇H₁₅Cl₂N₂O₂P · H₂O

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      Description
      OverviewA widely used anti-neoplastic agent that also displays immunosuppressant properties. Induces apoptotic cell death in rat thymus through the Fas/Fas ligand pathway.
      Catalogue Number239785
      Brand Family Calbiochem®
      SynonymsN,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA
      References
      ReferencesWang, G.J., and Cai, L. 1999. Mutat. Res. 427, 125.
      Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.
      Product Information
      CAS number6055-19-2
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₇H₁₅Cl₂N₂O₂P · H₂O
      Chemical formulaC₇H₁₅Cl₂N₂O₂P · H₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetFas/Fas ligand pathway
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSRP6157750
      Safety Information
      R PhraseR: 23/24/25-45-46-61

      Toxic by inhalation, in contact with skin and if swallowed.
      May cause cancer.
      May cause heritable genetic damage.
      May cause harm to the unborn child.
      S PhraseS: 22-36/37/39-45-53

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Avoid exposure - obtain special instructions before use.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsSolutions should be prepared fresh on the day of use.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      239785-1GM 04055977199567

      Documentation

      Cyclophosphamide Monohydrate - CAS 6055-19-2 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Cyclophosphamide Monohydrate - CAS 6055-19-2 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      239785

      Références bibliographiques

      Aperçu de la référence bibliographique
      Wang, G.J., and Cai, L. 1999. Mutat. Res. 427, 125.
      Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-September-2013 JSW
      SynonymsN,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA
      DescriptionA widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway.
      FormWhite solid
      CAS number6055-19-2
      RTECSRP6157750
      Chemical formulaC₇H₁₅Cl₂N₂O₂P · H₂O
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (30 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsSolutions should be prepared fresh on the day of use.
      Toxicity Toxic & Carcinogenic / Teratogenic
      Merck USA index14, 747
      ReferencesWang, G.J., and Cai, L. 1999. Mutat. Res. 427, 125.
      Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.