205531 Sigma-AldrichCA-074 Me - Calbiochem
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
More>> CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B. Less<<CA-074 Me - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Synonymes: Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester
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Aperçu
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Tableau de caractéristiques principal
| Empirical Formula |
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| C₁₉H₃₁N₃O₆ |
Prix & Disponibilité
| Référence | Disponibilité | Conditionnement | Qté | Prix | Quantité | |
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| 205531-1MG |
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Ampoule plast. | 1 mg |
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| Description | |
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| Overview | A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B. Reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro. |
| Catalogue Number | 205531 |
| Brand Family | Calbiochem® |
| Synonyms | Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₁₉H₃₁N₃O₆ |
| Chemical formula | C₁₉H₃₁N₃O₆ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | cathepsin B |
| Primary Target IC<sub>50</sub> | 2.24 nM against cathepsin B |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Dimensions |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Specifications |
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| Global Trade Item Number | |
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| Référence | GTIN |
| 205531-1MG | 07790788048433 |
Documentation
CA-074 Me - Calbiochem FDS
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CA-074 Me - Calbiochem Certificats d'analyse
| Titre | Numéro de lot |
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| 205531 |
Références bibliographiques
| Aperçu de la référence bibliographique |
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| Sever, N., et al. 2002. Biol. Chem. 383, 839. Authier, F., et al. 1999. J. Biol. Chem. 274, 33723. Hill, P.A., et al. 1994. J. Cell Biochem. 56, 118. Buttle, D.J., et al. 1992. Arch. Biochem. Biophys. 299, 377. |
Citations
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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