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MABT368 Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1

Detect Troponin T using this Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 validated for use in Western Blotting, Immunohistochemistry.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: TNNT2, CMD1D, CMH2, RCM3 UniProt Number: P45379
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MABT368
100 μg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT368
      DescriptionAnti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1
      Alternate Names
      • Troponin T, cardiac muscle
      • Cardiac muscle troponin T
      • cTnT
      • TnTc
      Background InformationTroponin T, cardiac muscle (UniProt P45379; also known as Cardiac muscle troponin T, cTnT, TnTc) is encoded by the TNNT2 (also known as CMD1D, CMH2, RCM3) gene (Gene ID 7139) in human. Troponin is a complex composed of three regulatory proteins, troponin C, troponin I, and troponin T). Troponin is found in both skeletal muscle and cardiac muscle where it plays an integral role in muscle contraction. Troponin T (TnT) is the component that binds tropomyosin, while troponin I (TnI) binds actin in thin myofilaments to hold the actin-tropomyosin complex in place. Three tissue TnT types exist, the slow skeletal troponin T1 encoded by the TNNT1 gene, the cardiac troponin T2 encoded by the TNNT2 gene, and the fast skeletal troponin T3 encoded by the TNNT3 gene.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2bκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Troponin T using this Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 validated for use in Western Blotting, Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Troponin T (Cardiac Muscle) in rat cardiac muscle tissue.
      Biological Information
      ImmunogenRecombinant human cardiac muscle troponin T internal fragment.
      EpitopeInternal.
      Clone9C2.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityExpected to react with human troponin T spliced isoforms 1-8 and 10, as well as all four of mouse troponin T spliced isoforms (Embryonic, A1, A2, and A3B isoforms; UniProt P50752) and both of rat troponin T spliced isoforms (Embryonic and Adult isoforms; UniProt P50753)
      IsotypeIgG2bκ
      Species Reactivity
      • Mouse
      • Rat
      Species Reactivity NoteMouse, Rat. Predicted to react with Human based on 100% sequence homology.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TNNT2
      • CMD1D
      • CMH2
      • RCM3
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~36 kDa observed. 35.8 kDa (isoform Embryonic), 35.0 kDa (isoform A1), 34.5 kDa (isoform A2), and 34.2 kDa (Isoform A3B) of mouse cardiac muscle troponin T spliced isoforms calculated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse heart tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Troponin T (Cardiac Muscle) in 10 µg of mouse heart tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      MABT368 04055977312966

      Documentation

      Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Anti-Troponin T (Cardiac Muscle) Antibody, clone 9C2.1 Certificats d'analyse

      TitreNuméro de lot
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 3164907
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3230498 3230498
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3419580 3419580
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3537581 3537581
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 3776089 3776089
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 4139147 4139147
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 - 4194266 4194266
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 -Q2640169 Q2640169
      Anti-Troponin T (Cardiac Muscle), clone 9C2.1 Monoclonal Antibody 3097982