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MABN359 Anti-SLC22A3 Antibody, clone 4H6.1

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MABN359
100 μg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN359
      ReplacesMABN1039
      DescriptionAnti-SLC22A3 Antibody, clone 4H6.1
      Alternate Names
      • Solute carrier family 22 member 3
      • Extraneuronal monoamine transporter
      • EMT
      • Organic cation transporter 3
      • SLC22A3
      Background InformationSolute carrier family 22 member 3 (UniProt O75751; also known as EMT, Extraneuronal monoamine transporterorganic cation transporter 3, Organic cation transporter 3) is encoded by the SLC22A3 (also known as EMTH, OCT3) gene (Gene ID 6581) in human. Solute carrier family 22 member 3 is a multi-transmembrane protein that mediates the outward transport and clearance of endogenous small organic cations as well as a wide array of drugs and environmental toxins. Known substrates for this transporter include histamine, serotonin, norepinephrine, dopamine and MPP+.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-SLC22A3 Antibody, clone 4H6.1, Cat. No. MABN359, is a highly specific mouse monoclonal antibody, that targets SLC22A3 and has been tested in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the C-terminal of human SLC22A3.
      EpitopeC-terminal
      Clone4H6.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SLC22A3
      • EMTH
      • OCT3
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~70 kDa observed. Due to glycosylation, the target band appears larger than the calculated molecular weight of 61.3 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human brain tissue lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected SLC22A3 in 10 µg of human brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      MABN359 04055977176971