adhesion+array+kit Search Results

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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

mTORC1 inhibition and ECM-cell adhesion-independent drug resistance via PI3K-AKT and PI3K-RAS-MAPK feedback loops.
Mammalian target of rapamycin (mTOR) serine threonine kinase is the enzyme that regulates cancer cell growth by altering nutrient supplies to cancer cells. The neuropeptide (proline-rich peptide 1 (PRP-1)), galarmin, produced by the brain neurosecretory cells is a mTOR kinase inhibitor with powerful 80% antiproliferative cytosta...
Document Type:

Reference

Product Catalog Number:

17-480
Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.
We performed a mutational analysis of the 19 disintegrin-metalloproteinases (ADAMs) genes in human cutaneous metastatic melanoma and identified eight to be somatically mutated in 79 samples, affecting 34% of the melanoma tumors analyzed. Functional analysis of the two frequently mutated ADAM genes, ADAM29 and ADAM7 demonstrated...
Document Type:

Reference

Product Catalog Number:

ECM540
Product Catalog Name:

ECM Cell Adhesion Array Kit, colorimetric
Effects of amelogenins on angiogenesis-associated processes of endothelial cells.
To study the effects of an amelogenin mixture on integrin-dependent adhesion, DNA synthesis and apoptosis of cultured human dermal microvascular endothelial cells and angiogenesis in an organotypic assay.
Document Type:

Reference

Product Catalog Number:

ECM532
Product Catalog Name:

α/β Integrin-mediated Cell Adhesion Array Combo Kit, colorimetic
Activin A regulates trophoblast cell adhesive properties: implications for implantation failure in women with endometriosis-associated infertility.
During implantation, the embryo adheres to the endometrium via cell adhesion molecules (CAMs) present on blastocyst trophectoderm and endometrial epithelial cells. CAMs, including integrins and extracellular matrix (ECM) ligands, are most likely regulated by hormones, cytokines and growth factors. We hypothesized first that acti...
Document Type:

Reference

Product Catalog Number:

ECM532
Product Catalog Name:

α/β Integrin-mediated Cell Adhesion Array Combo Kit, colorimetic
Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid.
The extracellular matrix (ECM) components play key roles in the multistep process of cancer growth and progression. Preclinical and clinical data show that bisphosphonates (BPs) may exert direct or indirect antitumoral effects. Despite proven efficiency in cancer treatment, the mechanism by which BPs can interfere with cancer pr...
Document Type:

Reference

Product Catalog Number:

ECM535
Product Catalog Name:

α/β Integrin-mediated Cell Adhesion Array Combo Kit, fluorimetric
Differential gene expression profiling of primary cutaneous melanoma and sentinel lymph node metastases.
Limited understanding of molecular mechanisms of metastasis in melanoma contributes to the absence of effective treatments. Increased knowledge of alterations in genes that underpin critical molecular events that lead to metastasis is essential. We have investigated the gene expression profiles of primary melanomas and melanoma...
Document Type:

Reference

Product Catalog Number:

MAB1789
Product Catalog Name:

Anti-Migration Inhibitory Factor Related Proteins 8 and 14 Antibody, clone AHN-17
Manipulating location, polarity, and outgrowth length of neuron-like pheochromocytoma (PC-12) cells on patterned organic electrode arrays.
In this manuscript, we describe a biocompatible organic electrode system, comprising poly(3,4-ethylenedioxythiophene) (PEDOT) microelectrode arrays on indium tin oxide (ITO) glass, that can be used to regulate the neuron type, location, polarity, and outgrown length of neuron-like cells (PC-12). We fabricated a PEDOT microelectr...
Document Type:

Reference

Product Catalog Number:

FAK100
Product Catalog Name:

Actin Cytoskeleton / Focal Adhesion Staining Kit
Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death.
Ataxin-3 (ATXN3) is a widely expressed protein that binds to ubiquitylated proteins, has deubiquitylating activity in vitro and is thought to modulate substrate degradation through the ubiquitin-proteasome pathway. Expansion of a polyglutamine tract in ATXN3 causes Machado-Joseph disease, a late-onset neurodegenerative disorder...
Document Type:

Reference

Product Catalog Number:

ECM530
Product Catalog Name:

α Integrin-mediated Cell Adhesion Array Kit, colorimetric
Development of micropost force sensor array with culture experiments for determination of cell traction forces.
Cell traction forces (CTFs) are critical for cell motility and cell shape maintenance. As such, they play a fundamental role in many biological processes such as angiogenesis, embryogenesis, inflammation, and wound healing. To determine CTFs at the sub-cellular level with high sensitivity, we have developed high density micropos...
Document Type:

Reference

Product Catalog Number:

FAK100
Product Catalog Name:

Actin Cytoskeleton / Focal Adhesion Staining Kit

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