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PF082 VEGFR1, Human, Recombinant, S. frugiperda

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PF082
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PF082-50UG
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      Plastic ampoule 50 μg
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      Description
      OverviewRecombinant, human VEGFR-1 expressed in S. frugiperda insect cells. Plays an important role in angiogenesis. Upon binding to VEGF, the receptor undergoes dimerization and is activated, leading to downstream signaling.
      Catalogue NumberPF082
      Brand Family Calbiochem®
      SynonymsVascular Endothelial Growth Factor Receptor-1, Flt-1, EMRK2
      References
      ReferencesHuang, K., et al. 2001. Int. J. Cell Biol. 33, 315.
      Soker, S., et al. 1998. Cell 92, 735.
      Kroll, J. and Waltenberger, J. 1997. J. Biol. Chem. 272, 32521.
      Kendall, R.L. and Thomas, K.A. 1993. PNAS. 90, 10705.
      Klagsbrun, M. and Soker, S. 1993. Current Biology 3, 699.
      Senger, D., et al. 1993. Cancer and Metastasis Rev. 12, 303.
      Brown, L., et al. 1992. Kidney International 42, 1457.
      Conn, G., et al. 1990. PNAS 87, 1323.
      Shibuya, M., et al. 1990. Oncogene 5, 519.
      Product Information
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, 300 mM NaCl, 50 µg BSA/µg of cytokine.
      Quality LevelMQ100
      Applications
      Data setup Error. Pagelet <collection_feature_application_id-PROLIF> not found.
      Biological Information
      Biological activityEC₅₀ of 15-30 ng/ml in a cell proliferation assay using human umbilical vein endothelial cells
      Purity≥90% by SDS-PAGE
      Species Reactivity
      • Human
      Physicochemical Information
      ContaminantsEndotoxin: ≤1 EU/µg cytokine
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      PF082-50UG 04055977207484