Millipore Sigma Vibrant Logo

569406 Stearoyl-CoA Desaturase 1 Inhibitor, MF-438 - Calbiochem

Overview

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
569406-10MG
Fulfillment and delivery delayed
Fulfillment and delivery delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Glass bottle 10 mg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewA cell-permeable, thiadiazole-pyridazine compound that acts as an inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC50 of 2.3 nM. In vivo, it exhibits an ED50 of 1-3 mg/kg, p.o., in mouse liver PD assays.
      Catalogue Number569406
      Brand Family Calbiochem®
      Synonyms2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole
      References
      ReferencesLeger, S., et al. 2010. Bioorg Med Chem Lett. 2, 499.
      Product Information
      FormOff-white powder
      Hill FormulaC₁₉H₁₈F₃N₅OS
      Chemical formulaC₁₉H₁₈F₃N₅OS
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationStearoyl-CoA Desaturase 1 Inhibitor, MF-438, CAS 921605-87-0, is a cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1; IC50 of 2.3 nM).
      Biological Information
      Purity≥99% by HPLC
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      569406-10MG 04055977190557