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491207 Novobiocin, Sodium Salt - CAS 1476-53-5 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
1476-53-5C₃₁H₃₅N₂O₁₁ · Na

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491207-10GM
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      Glass bottle 10 gm
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      Description
      OverviewDNA gyrase inhibitor used for the production of positively supercoiled plasma DNA. Inhibits retrovirus RNA-dependent DNA polymerases. Also a potent inhibitor of ADP ribosylation eliminates the wild-type pMG110 plasmid from E. coli.
      Catalogue Number491207
      Brand Family Calbiochem®
      References
      ReferencesMarcu, M.G., et al. 2000. J. Natl. Cancer Inst. 92, 242.
      Luhrmann, A., et al. 1998. Antimicrob. Agents Chemotherp. 42, 1911.
      Hooper, D.C., et al. 1984. Antimicrob. Agents Chemother. 25, 586.
      Lockshon, D., and Morris, D.R. 1983. Nucleic Acid. Res. 11, 2999.
      Sumiyoshi, Y., et al. 1983. J. Gen. Virol. 64, 2329.
      Staudenbauer, W.L. 1975. J. Mol. Biol. 96, 201.
      Product Information
      CAS number1476-53-5
      ATP CompetitiveN
      FormWhite to yellow solid
      Hill FormulaC₃₁H₃₅N₂O₁₁ · Na
      Chemical formulaC₃₁H₃₅N₂O₁₁ · Na
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary Targetretrovirus RNA-dependent DNA polymerases
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSRD5425000
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for 3 months at 4°C.
      Global Trade Item Number
      Catalogue Number GTIN
      491207-10GM 07790788050818