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FCABS352A4 Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT

Milli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: FLJ12581, FLJ40451, hNanog UniProt Number: Q9H9S0
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FCABS352A4
100 tests  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RFCRbAlexaFluor®488Polyclonal Antibody
      Description
      Catalogue NumberFCABS352A4
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT
      Alternate Names
      • Homeobox transcription factor Nanog
      • Nanog homeobox
      Background InformationNANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency, i.e., these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm).
      NANOG may be useful in the immunohistochemical diagnosis of tumors. NANOG is expressed in germ cells of the fetus and in some germ cell tumors of the gonads and central nervous system (CNS).
      References
      Product Information
      FormatAlexaFluor®488
      Control
      • 2102 Ep cells
      PresentationPurified rabbit polyclonal IgG conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenLinear peptide from mouse Nanog.
      EpitopeN-terminus
      HostRabbit
      SpecificityAntibody recognizes NANOG.
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteTested and passed on Human. Predicted to react with Mouse, Rat based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FLJ12581
      • FLJ40451
      • hNanog
      Purification MethodAntigen Affinity Purified
      UniProt Number
      UniProt SummaryTranscription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor, when overexpressed, promotes cells to enter into S phase and proliferation.
      Molecular Weight 34 kDa Calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using 2102 Ep cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      FCABS352A4 04053252750298

      Documentation

      Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2142679 2142679
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 1959253 1959253
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 1973231 1973231
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2042799 2042799
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2110558 2110558
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2270275 2270275
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - 2271190 2271190
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - NG1906885 NG1906885
      Milli-Mark Anti-Nanog-Alexa Fluor#174; 488, N-terminus - NRG1868516 NRG1868516
      Milli-Mark™ Anti-Nanog-Alexa Fluor 488, N-terminus -2679489 2679489
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies