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FCMAB199P Milli-Mark™ Anti-CD56-PE Antibody, clone C5.9

This Milli-Mark Anti-CD56-PE Antibody, clone C5.9 is validated for use in FC for the detection of CD56.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P13591
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FCMAB199P
100 tests  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMPhycoerythrinMonoclonal Antibody
      Description
      Catalogue NumberFCMAB199P
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD56-PE Antibody, clone C5.9
      Alternate Names
      • Neural cell adhesion molecule 1
      • NCAM-1
      Background InformationCD56 is a membrane glycoprotein which has multiple isoforms generated by alternative splicing from a single gene located on chromosome 11 (Costa, 1997). The core polypeptide is the 140 kDa isoform which can be variably glycosylated to produce mature species. The predominant isoform in NK and T cells is the transmembrane-anchored 140 kDa protein. In tissues, CD56 antigen is found in the cerebellum and cortex of the brain, and at neuromuscular junctions. This molecule is identical to the 140 kDa isoform of the neuronal cell adhesion molecule (N-CAM) (Poggi, 2002; Lanier, 1989). Additionally, CD56 is also present in certain large granular lymphocyte leukemias, small cell lung carcinomas, neural-derived tumors, myelomas, and myeloid leukemias (Poggi, 2002).
      Product Information
      FormatPhycoerythrin
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG2b conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
      Quality LevelMQ100
      Applications
      ApplicationThis Milli-Mark Anti-CD56-PE Antibody, clone C5.9 is validated for use in FC for the detection of CD56.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenHuman NK Cells
      CloneC5.9
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD56 antigen.
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryThis protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
      Molecular Weight 140 kDa (Poggi, 2002; Lanier, 1989)
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human lymphocytes
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB199P 04053252480355