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444286 MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem

The MMP-2 Inhibitor II, also referenced under CAS 869577-51-5, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane

Primary Target: MMP-2
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444286
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Overview

Key Spec Table

CAS #Empirical Formula
869577-51-5C₁₆H₁₇NO₆S₂

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444286-5MG
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      Description
      OverviewAn oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
      Catalogue Number444286
      Brand Family Calbiochem®
      Synonyms(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
      References
      ReferencesIkejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.
      Product Information
      CAS number869577-51-5
      FormWhite solid
      Hill FormulaC₁₆H₁₇NO₆S₂
      Chemical formulaC₁₆H₁₇NO₆S₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetMMP-2
      Primary Target K<sub>i</sub>2.4 µM
      Secondary targetMMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively)
      Purity≥97% by HPLC
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      444286-5MG 04055977186031