551476 Sigma-AldrichInSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem
InSolution™ Q-VD-OPh, Non-O-methylated, is a cell-permeable, irreversible, broad-spectrum inhibitor of caspases (IC₅₀ = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively).
More>> InSolution™ Q-VD-OPh, Non-O-methylated, is a cell-permeable, irreversible, broad-spectrum inhibitor of caspases (IC₅₀ = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: N-(2-Quinolyl)valyl-aspartyl-(2,6-difluorophenoxy)methyl Ketone
Recommended Products
-
107071 SAFC Neotame -
AQ132P Sigma-Aldrich Goat Anti-Rabbit IgG Antibody, F(ab')2, HRP conjugate -
110049 Supelco Molybdenum Test -
71570 Sigma-Aldrich pET-51 Ek/LIC Vector Kit - Novagen -
ZF3000143 Milli-Q ZF3000143 -
14-777 Sigma-Aldrich Plk1 Protein, active, 10 µg -
07-030-AF488 Sigma-Aldrich Anti-dimethyl-Histone H3 (Lys4) Antibody, Alexa Fluor® 488 conjugate -
VPPS102NB1 Millipore Viresolve® Pro Modus 1.2 Shield -
AP11/130X100-3D5 Millipore NovaSeptum holder General Sampling, 1-
port Ø13 mm TC25 -
70839 Sigma-Aldrich Origami™ B(DE3)pLysS Competent Cells - Novagen
Overview
Key Spec Table
| Empirical Formula |
|---|
| C₂₆H₂₅F₂N₃O₆ |
Pricing & Availability
| Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
|---|---|---|---|---|---|---|
| 551476-1MG |
|
Plastic ampoule | 1 mg |
|
— | |
| 551476-5MG |
|
Glass bottle | 5 mg |
|
— |
| References | |
|---|---|
| References | Braun, J.S., et al. 2007. Exp. Neurol. 206, 183. Caserta, T.M., et al. 2003. Apoptosis 8, 345. Rebbaa, A., et al. 2003. Oncogene 22, 2805. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Liquid |
| Formulation | Supplied as a 10 mM (1 mg/195 µl) solution in DMSO. |
| Hill Formula | C₂₆H₂₅F₂N₃O₆ |
| Chemical formula | C₂₆H₂₅F₂N₃O₆ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | caspase-1 |
| Primary Target IC<sub>50</sub> | 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Peptide Sequence | Q-Val-Asp-CH₂-OPh |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 551476-1MG | 04055977268898 |
| 551476-5MG | 04055977268904 |