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14-1067 Human Recombinant MeCP2 (methyl-CpG-binding protein 2)

Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: DNA-binding Proteins
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14-1067
10 µg  
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      Overview

      Replacement Information
      Description
      Catalogue Number14-1067
      DescriptionHuman Recombinant MeCP2 (methyl-CpG-binding protein 2)
      OverviewHuman recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells and purified by Fast Protein Liquid Chromatography (FPLC).
      Background InformationMeCP2 (methyl-CpG-binding protein 2) binds methylated CpG sequences in double-stranded DNA resulting in the suppression of transcription. This protein is likely to be involved in the repression of multiple genes. Consistent with this role, mutations of MeCP2 are linked to Rett syndrome, a progressive neurological disorder that is one of the most common causes of mental retardation in females.
      References
      Product Information
      PresentationIn a buffer containing 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
      Quality LevelMQ100
      Applications
      ApplicationHuman recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA
      Key Applications
      • DNA-binding Proteins
      Biological Information
      Concentration0.5 µg/µL
      PurityGreater than 95% purity by SDS PAGE
      Molecular Weight50.2 kDa including histidine tag
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable at -80ºC for 6 months from date of receipt.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-1067 04053252957437

      Documentation

      Human Recombinant MeCP2 (methyl-CpG-binding protein 2) SDS

      Title

      Safety Data Sheet (SDS) 

      Human Recombinant MeCP2 (methyl-CpG-binding protein 2) Certificates of Analysis

      TitleLot Number
      Human Recombinant MeCP2 - QVP1312092 QVP1312092
      Human Recombinant MeCP2 - VP1908120 VP1908120
      Human Recombinant MeCP2 - VP2001102 VP2001102
      Human Recombinant MeCP2 - VP2008120 VP2008120
      Human Recombinant MeCP2 - VP2106240 VP2106240
      Human Recombinant MeCP2 - VP22010500 VP22010500
      Human Recombinant MeCP2 - VP2205230 VP2205230
      Human Recombinant MeCP2 - VP2304100 VP2304100
      Human Recombinant MeCP2 - VP2401080 VP2401080
      Human Recombinant MeCP2 - VP2407100 VP2407100
      Show more

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