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AB9842 Anti-phospho-Munc-18 (Ser515) Antibody

This Anti-phospho-Munc-18 (Ser515) Antibody is validated for use in WB for the detection of phospho-Munc-18 (Ser515).

Anti-phospho-Munc-18 (Ser515) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Synapse & Synaptic Biology Gene Symbol: Stxbp1, Unc18a UniProt Number: P61765
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AB9842
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9842
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-phospho-Munc-18 (Ser515) Antibody
      Alternate Names
      • ANC18HA
      • Munc18-1
      • n-Sec1
      • nSsec1
      • NSEC1A
      • p67
      • Protein unc-18 homolog 1
      • Protein unc-18 homolog A
      • rbSec1
      • rbSec1A
      • rbSec1B
      • Sec1
      • Syntaxin-binding protein 1
      • Unc18-1
      • Unc-18A
      • Unc-18 homolog
      • Stxbp1
      • Unc18a
      References
      Product Information
      FormatAffinity Purified
      PresentationLiquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug/mL BSA and 50% glycerol.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-phospho-Munc-18 (Ser515) Antibody is validated for use in WB for the detection of phospho-Munc-18 (Ser515).
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenSynthetic peptide corresponds to sequence surrounding the phosphoserine 515 site of rat Munc-18.
      HostRabbit
      SpecificityMunc-18, phospho Serine 515. The antibody recognizes a protein of ~65 kDa corresponding to Munc-18, phospho Serine 515 in lysates from rat cortex. Immunolabeling is blocked by the phosphopeptide used as the immunogen but not the corresponding non-phosphopeptide.
      Species Reactivity
      • Rat
      Species Reactivity NoteThe immunogen has 100% homology with human, mouse, non-human primates, bovine, canine, chicken and Xenopus.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Stxbp1
      • Unc18a
      Modifications
      • Phosphorylation
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P61765 # May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
      SIZE: 594 amino acids; 67569 Da
      SUBCELLULAR LOCATION: Cytoplasm. Membrane; Peripheral membrane protein.
      TISSUE SPECIFICITY: Brain and spinal cord. Highly enriched in axons.
      SIMILARITY: SwissProt: P61765 ## Belongs to the STXBP/unc-18/SEC1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20degC in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9842 04053252741050