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ABN262 Anti-Trypsin-3 Antibody

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ABN262
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN262
      DescriptionAnti-Trypsin-3 Antibody
      Alternate Names
      • Trypsin-3
      • Brain trypsinogen
      • Mesotrypsinogen
      • Serine protease 3
      • Serine protease 4
      • Trypsin III
      • Trypsin IV
      Background InformationTrypsin-3 is also called Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, and Trypsin IV and belongs to the peptidase S1 family. Trypsin-3 is a digestive protease that specifically degrades trypsin inhibitors and may be involved in the processing of defensins, including DEFA5, in the ileum. Trypsin-3 is expressed in pancreas, brain and in Paneth cells, at the base of small intestinal crypts.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human pancreas tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Trypsin-3 Antibody is a highly specific rabbit polyclonal antibody, that targets Trypsin & has been tested in western blotting & IHC (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Trypsin-3 in human pancreatic, cerebellum, and thalamus tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the human Trypsin-3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Other homologies: Rat (82% sequence homology), Mouse (72% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PRSS3
      • PRSS4
      • TRY3
      • TRY4
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~26 kDa observed. Four isoforms are known to exist due to alternative splicing.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human pancreas tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected Trypsin-3 in 10 µg of human pancreas tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN262 04053252908545