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ABF199 Anti-TIM-1 Antibody

Anti-TIM-1 Antibody is a highly specific rabbit polyclonal antibody, that targets T-cell immunoglobulin & mucin domain-containing protein 1 & has been tested in western blotting, IHC & Immunofluorescence.

Anti-TIM-1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: HAVCR1 UniProt Number: Q96D42
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ABF199
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF199
      DescriptionAnti-TIM-1 Antibody
      Alternate Names
      • Hepatitis A virus cellular receptor 1
      • HAVcr-1
      • Kidney injury molecule 1
      • KIM-1
      • T-cell immunoglobulin and mucin domain-containing protein 1
      • TIMD-1
      • T-cell membrane protein 1
      • TIM-1
      • TIM
      • KIM1
      • TIM1
      • TIMD1
      Background InformationT-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1, TIM-1, TIM, TIM1, TIMD1), also known as Hepatitis A virus cellular receptor 1 (HAVcr-1) and Kidney injury molecule 1(KIM-1, KIM1), may play an important role in T-helper cell development and the regulation of asthma and allergic diseases. In the case of human hepatitis A virus (HHAV) infection, TIM-1 functions as a cell-surface receptor for the virus, through which the hepatitis A virus can gain entry into a cell. Additional evidence implies that it may play a role in kidney injury and repair. TIM-1 is widely expressed, with highest levels in kidney and testis. It is also expressed by activated CD4+ T-cells during the development of helper T-cells responses. Furthermore, TIM-1 is expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human uterus tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-TIM-1 Antibody is a highly specific rabbit polyclonal antibody, that targets T-cell immunoglobulin & mucin domain-containing protein 1 & has been tested in western blotting, IHC & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 10 µg/mL from a representative lot detected TIM-1 in human uterus tissue.

      Immunofluorescence Analysis: 20 µg/mL from a representative lot detected TIM-1 in human uterus tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human TIM-1.
      EpitopeN-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the N-terminus of TIM-1.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • HAVCR1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~48 kDa observed. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human uterus tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected TIM-1 in 15 µg of human uterus tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABF199 04053252910098

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies