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MABC98 Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1

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MABC98
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC98
      DescriptionAnti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1
      Alternate Names
      • Sphingosine 1-phosphate receptor 5
      • S1P receptor 5
      • S1P5
      • Endothelial differentiation G-protein-coupled receptor 8
      • Sphingosine 1-phosphate receptor Edg-8
      • S1P receptor Edg-8
      Background InformationSphingosine 1-phosphate receptor 5 (S1PR5 or S1P5), otherwise known as EDG8, is a G-protein coupled receptor which is activated by the lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi/0 alpha and G12 signaling pathways. S1P5 is highly abundant in the brain, particularly in the corpus callosum, but S1P5 has also been detected in the spleen, placenta, lung, aorta, and peripheral blood leukocytes. In the brain, it regulates the transformation of radial glial cells into astrocytes, and the migration of oligodendrocyte precursor cells during development.
      References
      Product Information
      FormatPurified
      Control
      • Daudi cell lysate
      PresentationPurified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Sphingosine 1-phosphate receptor 5 (S1P5) using this Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 validated for use in Western Blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 5 in normal human cerebellum and normal placenta tissue.
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 5 (S1P5).
      Clone13F9.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse based on immunogen design.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • S1PR5
      • EDG8
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~42 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in Daudi cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected Sphingosine 1-phosphate receptor 5 in 10 µg of Daudi cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC98 04053252694257

      Documentation

      Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 Certificates of Analysis

      TitleLot Number
      Anti-Sphingosine 1-phosphate -2753831 2753831
      Anti-Sphingosine 1-phosphate -2821239 2821239
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 3082668
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 2467146 2467146
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3228349 3228349
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3259078 3259078
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3439728 3439728
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3991484 3991484
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - Q2037261 Q2037261
      Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 -2521710 2521710

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies