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ABN333 Anti-Neurotrypsin Antibody

Detect the Neurotrypsin protein using this Anti-Neurotrypsin validated for use in WB & IHC.

Anti-Neurotrypsin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: PRSS12 UniProt Number: P56730
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ABN333
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN333
      DescriptionAnti-Neurotrypsin Antibody
      Alternate Names
      • Neurotrypsin
      • Leydin
      • Motopsin
      • Serine protease 12
      Background InformationNeurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions. These functions include axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
      References
      Product Information
      FormatAffinity Purified
      Control
      • mouse testis tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationDetect the Neurotrypsin protein using this Anti-Neurotrypsin validated for use in WB & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blot Analysis: 1 µg/mL from a representative lot detected Neurotrypsin in 10 µg/mL of rat testis tissue lysate.

      Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Neurotrypsin in human midbrain and rat cerebellum tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Neurotrypsin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • PRSS12
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~97 kDa observed. Uncharacterized bands may appear at ~13 kDa, ~38 kDa, and ~43 kDa in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse testis tissue lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected Neurotrypsin in 10 µg/mL of mouse testis tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN333 04053252831133