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MABT94-100UG Anti-Myomesin-2 Antibody, clone 3B9.3

Anti-Myomesin-2, clone 3B9.3, Cat. No. MABT94, is a mouse monoclonal antibody that detects human Myomesin-2 and has been tested for use in Western Blotting.

Anti-Myomesin-2 Antibody, clone 3B9.3 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Gene Symbol: MYOM2 UniProt Number: P54296
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MABT94-100UG
100 μg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT94-100UG
      DescriptionAnti-Myomesin-2 Antibody, clone 3B9.3
      Alternate Names
      • Myomesin-2
      • 165 kDa connectin-associated protein
      • 165 kDa titin-associated protein
      • M-protein
      • Myomesin family member 2
      Background InformationMyomesin-2 (UniProt: P54296; also known as 165 kDa connectin-associated protein, 165 kDa titin-associated protein, M-protein, Myomesin family member 2) is encoded by the MYOM2 gene (Gene ID: 9172) in human. Myomesin-2 is a major component of the vertebrate myofibrillar M band and is mainly expressed in fast fibers. It binds myosin, titin, and light meromyosin in a dose-dependent manner. Its primary function is to upkeep M-band filament lattice. It has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Myomesin-2 is shown to interact with dysferlin, a protein that aids in repairing the sarcolemma when it is damaged or torn due to muscle strain and assists in myofibril stability.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationAnti-Myomesin-2, clone 3B9.3, Cat. No. MABT94, is a mouse monoclonal antibody that detects human Myomesin-2 and has been tested for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant fragment corresponding to 154 amino acids from the N-terminal region of human Myomesin-2.
      Clone3B9.3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone 3B9.3 detects human muscle Myomesin-2. It targets an epitope with in the N-terminal half.
      IsotypeIgG2aλ
      Species Reactivity
      • Human
      Species Reactivity NoteHuman.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MYOM2
      Purification MethodProtein G purified
      UniProt Number
      Molecular Weight~165 kDa observed; 164.90 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human skeletal muscle tissue lysate.

      Western Blotting Analysis: 0.05 µg/mL of this antibody detected Myomesin-2 in human skeletal muscle tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABT94-100UG 04054839519413