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MABS816 Anti-MAP3K2, clone 4B4 Antibody

Anti-MAP3K2, clone 4B4 Antibody is an antibody against MAP3K2 for use in Western Blotting, Immunocytochemistry, ELISA.

Anti-MAP3K2, clone 4B4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: MAP3K2, MAPKKK2, MEKK2 UniProt Number: Q9Y2U5
MABS816
100 µL  
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      Overview

      Replacement Information

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, ELISAMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABS816
      Replaces04-378
      DescriptionAnti-MAP3K2, clone 4B4 Antibody
      Alternate Names
      • Mitogen-activated protein kinase kinase kinase 2
      • MAP3K2
      Background InformationMitogen-activated protein kinase kinase kinase 2 (MAP3K2) is a member of serine/threonine protein kinase family. MAP3K2 preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. MAP3K2 has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-MAP3K2, clone 4B4 Antibody is an antibody against MAP3K2 for use in Western Blotting, Immunocytochemistry, ELISA.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • ELISA
      Application NotesImmunocytochemistry Analysis (ICC): A 1:200-1,000 dilution from a representative lot detected MAP3K2 in 3T3-L1 cells.

      ELISA: A representative lot detected control antigen (100 ng) and antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
      Biological Information
      ImmunogenPurified recombinant fragment of human ERK3 expressed in E. Coli. 
      Clone4B4
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • MAP3K2
      • MAPKKK2
      • MEKK2
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~58 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HEK293 and MAP3K2 -hIgGFc transfected HEK293 cell lysate.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected MAP3K2 in hIgGFc transfected HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS816 04055977172348