Millipore Sigma Vibrant Logo

MABN481 Anti-Lipocalin-2 Antibody, clone PA348-26.3.5

Detect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: LCN2, HNL, NGAL UniProt Number: P80188
View Products on Sigmaaldrich.com
MABN481
100 µg  
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Fulfillment and delivery delayed Fulfillment and delivery delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Special Offers

      100% Performance Guaranteed

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, ELISAMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN481
      DescriptionAnti-Lipocalin-2 Antibody, clone PA348-26.3.5
      Alternate Names
      • ngal
      • neutrophil lipocalin
      • siderocalin
      • Neutrophil gelatinase-associated lipocalin
      • NGAL
      • 25 kDa alpha-2-microglobulin-related subunit of MMP-9
      • Lipocalin-2
      • Oncogene 24p3
      • Siderocalin LCN2
      • p25
      Background InformationLipocalin-2 (LCN2) (also known as Neurophil Gelatinase-Associated Lipocalin or NGAL) belongs to a superfamily of lipocalins, a collection of small, diversely functional, extracellular proteins. Lipocalin-2 is secreted from neutrophil granules in three different forms: a monomer of 25 kDa, a disulfide-linked homodimer at 46 kDa, and a disulfide-linked heterodimer with MMP-9 at 135-kDa. It is widely known to induce development of kidney epithelia, to bind and traffic iron, and to act as a molecular signal under inflammatory conditions, such as Crohn’s Disease. Multiple carcinoma studies have also shown elevated expression levels of Lipocalin-2 in several different human tumors affecting such organs as colon, lung, breast, ovaries, and pancreas. Additionally, there has been great interest in this protein as a possible marker for onset of Acute Kidney Injury following cardiac surgery, the progression of Chronic Kidney Disease (CKD), and the survival chances of patients with Chronic Heart Failure (CHF).
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • ELISA
      Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Lipoacalin-2 in human bone marrow and stomach tissue lysate.

      ELISA Analysis: A representative lot from an independent laboratory detected Lipocalin-2 in indirect ELISA.
      Biological Information
      ImmunogenRecombinant protein corresponding to human Lipocalin-2.
      ClonePA348-26.3.5
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LCN2
      • HNL
      • NGAL
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~23 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human lung tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected Lipocalin-2 in 10 µg of human lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      MABN481 04053252923746