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MABN481 Anti-Lipocalin-2 Antibody, clone PA348-26.3.5

Detect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: LCN2, HNL, NGAL UniProt Number: P80188
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MABN481
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, ELISAMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN481
      DescriptionAnti-Lipocalin-2 Antibody, clone PA348-26.3.5
      Alternate Names
      • ngal
      • neutrophil lipocalin
      • siderocalin
      • Neutrophil gelatinase-associated lipocalin
      • NGAL
      • 25 kDa alpha-2-microglobulin-related subunit of MMP-9
      • Lipocalin-2
      • Oncogene 24p3
      • Siderocalin LCN2
      • p25
      Background InformationLipocalin-2 (LCN2) (also known as Neurophil Gelatinase-Associated Lipocalin or NGAL) belongs to a superfamily of lipocalins, a collection of small, diversely functional, extracellular proteins. Lipocalin-2 is secreted from neutrophil granules in three different forms: a monomer of 25 kDa, a disulfide-linked homodimer at 46 kDa, and a disulfide-linked heterodimer with MMP-9 at 135-kDa. It is widely known to induce development of kidney epithelia, to bind and traffic iron, and to act as a molecular signal under inflammatory conditions, such as Crohn’s Disease. Multiple carcinoma studies have also shown elevated expression levels of Lipocalin-2 in several different human tumors affecting such organs as colon, lung, breast, ovaries, and pancreas. Additionally, there has been great interest in this protein as a possible marker for onset of Acute Kidney Injury following cardiac surgery, the progression of Chronic Kidney Disease (CKD), and the survival chances of patients with Chronic Heart Failure (CHF).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • ELISA
      Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Lipoacalin-2 in human bone marrow and stomach tissue lysate.

      ELISA Analysis: A representative lot from an independent laboratory detected Lipocalin-2 in indirect ELISA.
      Biological Information
      ImmunogenRecombinant protein corresponding to human Lipocalin-2.
      ClonePA348-26.3.5
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LCN2
      • HNL
      • NGAL
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~23 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human lung tissue lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected Lipocalin-2 in 10 µg of human lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN481 04053252923746

      Documentation

      Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 Certificates of Analysis

      TitleLot Number
      Anti-Lipocalin-2, clone PA348-26.3.5 - 3748839 3748839
      Anti-Lipocalin-2, clone PA348-26.3.5 - Q2273107 Q2273107
      Anti-Lipocalin-2, clone PA348-26.3.5 -2687873 2687873
      Anti-Lipocalin-2, clone PA348-26.3.5 -2774080 2774080
      Anti-Lipocalin-2, clone PA348-26.3.5 Monoclonal Antibody 2985080
      Anti-Lipocalin-2, clone PA348-26.3.5 Monoclonal Antibody 3101060
      Anti-Lipocalin-2, clone PA348-26.3.5, Monoclonal Antibody 2841535

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies