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MABN319 Anti-Coronin-1A, clone 2E4.1 Antibody

Anti-Coronin-1A, clone 2E4.1 Antibody is an antibody against Coronin-1A for use in Immunohistochemistry and Immunocytochemistry.

Anti-Coronin-1A, clone 2E4.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: CORO1A, CORO1 UniProt Number: P31146
MABN319
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN319
      DescriptionAnti-Coronin-1A, clone 2E4.1 Antibody
      Alternate Names
      • Coronin-1A
      • Coronin-like protein A
      • Clipin-A
      • Coronin-like protein p57
      • Tryptophan aspartate-containing coat protein
      • TACO
      Background InformationCoronin-1A (also known as clipin-A, coronin-1, coronin-like protein, Acoronin-like protein p57, tryptophan aspartate-containing coat protein) is a cytoplasmic protein encoded by the CORO1A gene in human (also known as CLABP, CLIPINA, HCORO1, IMD8, TACO). It is a member of the WD repeat protein family of proteins that are reported to be involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Coronin-1A is reported to be a component of the phagosome coat that is normally released prior to maturation into lysosomes. Mycobacteria are reported to evade host defense by recruiting and retaining coronin-1A on phagosomes, while in coronin-1A-lacking macrophages, mycobacteria are readily transported to lysosomes for degradation (PMID 10338208).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Coronin-1A, clone 2E4.1 Antibody is an antibody against Coronin-1A for use in Immunohistochemistry and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Coronin-1A in human cerebellum and human thalamus tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Coronin-1A.
      Clone2E4.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CORO1A
      • CORO1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~51 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Jurkat cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Coronin-1A in 10 µg of Jurkat cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN319 04055977159325

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies