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ABE601 Anti-CPEB1 Antibody

Detect Cytoplasmic polyadenylation element-binding protein 1 using this rabbit polyclonal antibody, Anti-CPEB1 Antibody validated for use in western blotting.

Anti-CPEB1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: RNA Metabolism & Binding Proteins Gene Symbol: CPEB1, CPEB UniProt Number: Q9BZB8
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ABE601
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE601
      DescriptionAnti-CPEB1 Antibody
      Alternate Names
      • Cytoplasmic polyadenylation element-binding protein 1
      • CPE-BP1
      • CPE-binding protein 1
      • h-CEBP
      • hCPEB-1
      Background InformationCytoplasmic polyadenylation element-binding protein 1 (CPE-BP1, CPEB1) is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region and is found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Rat brain tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Cytoplasmic polyadenylation element-binding protein 1 using this rabbit polyclonal antibody, Anti-CPEB1 Antibody validated for use in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human CPEB1.
      EpitopeN-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the N-terminus of CPEB1.
      Species Reactivity
      • Rat
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • CPEB1
      • CPEB
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~65 kDa observed. Uniprot describes 2 isoforms at ~54 kDa, one isoform at ~62 kDa, and one isoform at ~63 kDa. Uncharacterized bands may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected CPEB1 in 15 µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE601 04053252905438