Qty	Catalogue Number	Ordering Description	Qty/Pack	List Price
			96-Well Plate

Qty	Catalogue Number	Ordering Description	Qty/Pack	List Price
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

100030 Acetonitrile

Acetonitrile gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur. Acetonitrile CAS 75-05-08, molar mass 41.05 g/mol, and chemical formula CH₃CN.

Acetonitrile MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
Brochures
Technical Information
Application Notes

Synonyms: ACN, Methyl cyanide, Ethyl nitrile, Cyanomethane

CAS #: 75-05-8 EC Number: 200-835-2 Molar Mass: 41.05 g/mol Chemical Formula: CH₃CN Hill Formula: C₂H₃N Grade: Reag. Ph Eur

View Products on Sigmaaldrich.com

Recommended Products

Overview

Replacement Information

Key Spec Table

CAS #	EC Number	Hill Formula	Chemical Formula	Molar Mass	Grade Value
75-05-8	200-835-2	C₂H₃N	CH₃CN	41.05 g/mol	Reag. Ph Eur

Pricing & Availability

Catalogue Number	Availability	Packaging	Qty/Pack	Price	Quantity
1000302510	Retrieving availability... — Fulfillment and delivery delayed In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Fulfillment and delivery delayed In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Glass bottle	2.5 l	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
1000304008	Retrieving availability... — Fulfillment and delivery delayed In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Fulfillment and delivery delayed In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Glass bottle	4 l	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
1000305005	Retrieving availability... — Fulfillment and delivery delayed In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Fulfillment and delivery delayed In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service		5 l	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
1000305024	Retrieving availability... — Fulfillment and delivery delayed In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Fulfillment and delivery delayed In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service		24 PC	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites
1000309915	Retrieving availability... — Fulfillment and delivery delayed In Stock Discontinued Limited Quantities Available Availability to be confirmed Login to See Inventory In Stock Fulfillment and delivery delayed In Stock Remaining : Will advise Remaining : Will advise Will advise Contact Customer Service Contact Customer Service Contact Customer Service Contact Customer Service	Container Steel - IBC	1000 l	Retrieving price... Price could not be retrieved Minimum Quantity is a multiple of Maximum Quantity is Upon Order Completion More Information You Saved () — Request Pricing Login to See Your Pricing	Check Availability —	Add To Favorites Add To Favorites Added To My Favorites

Description
Catalogue Number	100030
Synonyms	ACN, Methyl cyanide, Ethyl nitrile, Cyanomethane
Overview	With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.

References

Product Information
CAS number	75-05-8
EC index number	608-001-00-3
EC number	200-835-2
Grade	Reag. Ph Eur
Hill Formula	C₂H₃N
Chemical formula	CH₃CN
Molar Mass	41.05 g/mol
HS Code	2926 90 99
Structure formula Image
Quality Level	MQ200

Applications
Application	Acetonitrile gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur. Acetonitrile CAS 75-05-08, molar mass 41.05 g/mol, and chemical formula CH₃CN.

Biological Information

Physicochemical Information
Boiling point	81.6 °C (1013 hPa)
Density	0.78 g/cm3 (20 °C)
Explosion limit	3.0 - 17 %(V)
Flash point	2 °C
Ignition temperature	524 °C
Melting Point	-45.7 °C
Vapor pressure	98.64 hPa (20 °C)

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H225: Highly flammable liquid and vapour. H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled. H319: Causes serious eye irritation.
Precautionary Statement(s)	P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal Word	Danger
RTECS	AL7700000

Safety Information

Product Usage Statements

Storage and Shipping Information

Packaging Information

Transport Information
Declaration (railroad and road) ADR, RID	UN 1648 , 3, II
Declaration (transport by air) IATA-DGR	UN 1648 , 3, II
Declaration (transport by sea) IMDG-Code	UN 1648 , 3, II

Supplemental Information

Specifications
Purity (GC)	≥ 99.9 %
Identity (IR)	conforms
Evaporation residue	≤ 2.0 mg/l
Water	≤ 0.02 %
Color	≤ 10 Hazen
Density (d 20 °C/20 °C)	0.78
Refractive index (n 20/D)	1.344
Boiling range (80-82°C)	≥ 95 % (v/v)
Acidity	≤ 0.0002 meq/g
Alkalinity	≤ 0.0002 meq/g
Gradient grade (at 210 nm)	≤ 1.0 mAU
Gradient grade (at 254 nm)	≤ 0.5 mAU
Fluorescence (as quinine at 254 nm)	≤ 1.0 ppb
Fluorescence (as quinine at 365 nm)	≤ 0.5 ppb
Transmission (at 193 nm)	≥ 60 %
Transmission (at 195 nm)	≥ 80 %
Transmission (from 230 nm)	≥ 98 %
Absorbance (at 200 nm)	≤ 0.1
Absorbance (from 240 nm)	≤ 0.01
Filtered by 0.2 µm filter. Suitable for UPLC / UHPLC / Ultra HPLC - instruments. Conforms to Reag. ChP; Acetonitrile for Chromatography and Acetonitrile R1 according to Reag. Ph Eur; to the requirements of ACS reagent grade for liquid chromatographic suitability.

Global Trade Item Number
Catalogue Number	GTIN
1000302510	04027269137427
1000304008	04027269299378
1000305005	04054839477409
1000305024	04054839705984
1000309915	04065265341554

Documentation

Acetonitrile SDS

Title
Safety Data Sheet (SDS)

Acetonitrile Certificates of Analysis

Product Number	Packaging	Specification	Lot Number
1000302510	Glass bottle	PDF Specification Document	Enter Lot Number
1000304008	Glass bottle	PDF Specification Document	Enter Lot Number
1000305005		PDF Specification Document	Enter Lot Number
1000305024		PDF Specification Document	Enter Lot Number
1000309915	Container Steel - IBC	PDF Specification Document	Enter Lot Number

Brochure

Title
UHPLC 2 - Guidelines for high throughput separations

Technical Info

Title
Atovaquone Oral Suspension (USP)
Complete Monograph Methods - Solutions for regulated Pharmaceutical Instrumental Analysis Methods with HPLC, FTIR, KF, AAS and ICP 2015 -1
Esomeprazole (USP)
Fexofenadine and Related Substances (USP)
Food Safety and Food Quality Control - Beat your own record!
Guaifenesin USP Method Guaifenesin Assay
Lansoprazole - USP Method Lansoprazole RS
Letrozole - USP Method Letrozole RS - USP Method Letrozole Assay
Olmesartan Medoxomil (USP)
Pantoprazole Sodium - USP Method Pantoprazole Sodium RS - USP Method Pantoprazole Sodium Assay

Application Notes

Title
Antifungal medication (Standards) - separation of Itraconazole & impurities - using a Chromolith® HighResolution RP-18e column
Eye medication (Standards) - separation of Bimatoprost & free acid - using a Chromolith® HighResolution RP-18e column
Eye medication (Standards) - separation of Travoprost & free acid - using a Chromolith® HighResolution RP-18e column
Fungicides (E232 Standards) - separation of Phenylphenols - using a Chromolith® HighResolution RP-18e column
Nootropic drug (Standards) - separation of Levetiracetam and Caffeine - using a Chromolith® HighResolution RP-18e column
Organic acids (Standards) - separation of 9 Carboxylic and Aromatic acids - using a Chromolith® HighResolution RP-18e column
Peptides & Proteins (Standards) - separation of Lysozyme - using a Chromolith® HighResolution RP-18e column
Steroids (Standards) - separation of Prednisolone, Estradiol, Ethinyl-Estradiol, Estrone and Progesterone - using a Chromolith® HighResolution RP-18e column

Accessories (Primary)

Catalogue Number

Description

106710

Withdrawal system for stainless steel barrels and drums

Show Pricing & Availability

Accessories (Secondary)

Catalogue Number

Description

108801

Bottle key