Millipore Sigma Vibrant Logo

574775 Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem

Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
72741-87-8C₈H₁₅NO₃

Preis & Verfügbarkeit

Bestellnummer VerfügbarkeitVerpackung St./Pkg. Preis Menge
574775-500UG
Verfügbarkeit wird abgerufen...
Eingeschränkte Verfügbarkeit
Eingeschränkte Verfügbarkeit
Lieferbar 
Produkt wurde eingestellt
Begrenzter Lagerbestand
Bestätigung der Verfügbarkeit erforderlich
    Restmenge: Angebot folgt
      Restmenge: Angebot folgt
      Bitte erfragen
      Kontakt zum Kundenservice
      Contact Customer Service

      Kst.-Ampulle 500 μg
      Preis wird abgerufen...
      Preis nicht abrufbar
      Die Mindestmenge muss ein Vielfaches sein von
      Maximum Quantity is
      Bei Bestätigung Weitere Informationen
      Sie haben () gespart
       
      Bitte erfragen
      Description
      OverviewReversible active-site inhibitor of lysosomal α-mannosidase. Inhibits the growth of tumors and prevents metastasis in murine models. Blocks the processing of high mannose to complex type oligosaccharides.
      Catalogue Number574775
      Brand Family Calbiochem®
      Synonyms(1S,2S,8R,8aR)-Trihydroxyindolizidine, 8aβ-Indolizidine-1α,2α,8β-triol
      References
      ReferencesMochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
      Elbein, A.D. 1983. Methods Enzymol. 98, 135.
      Product Information
      CAS number72741-87-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₈H₁₅NO₃
      Chemical formulaC₈H₁₅NO₃
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetLysosomal α-mannosidase
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      574775-500UG 04055977189711

      Documentation

      Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem Analysenzertifikate

      TitelChargennummer
      574775

      Literatur

      Übersicht
      Mochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
      Elbein, A.D. 1983. Methods Enzymol. 98, 135.

      Literaturstellen

      Titel
    • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
    • Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      Synonyms(1S,2S,8R,8aR)-Trihydroxyindolizidine, 8aβ-Indolizidine-1α,2α,8β-triol
      DescriptionReversible active-site inhibitor of lysosomal α-mannosidase. Inhibits the growth of tumors and prevents metastasis in murine models. Blocks the processing of high mannose to complex type oligosaccharides.
      FormWhite solid
      CAS number72741-87-8
      Chemical formulaC₈H₁₅NO₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (5 mg/ml), H₂O (1 mg/ml), or Chloroform
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Harmful
      ReferencesMochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
      Elbein, A.D. 1983. Methods Enzymol. 98, 135.
      Citation
    • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.