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14-647M SGK3 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human SGK3 amino acids 119-end, for use in Kinase Assays.

SGK3 Protein, active, 250 µg: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
14-647M
250 µg  Also available in 10 μg size (cat#14-647) and in bulk (cat# 14-647-K).
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      Übersicht

      Replacement Information
      Description
      Catalogue Number14-647M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionSGK3 Protein, active, 250 µg
      OverviewN-terminal 6His-tagged, recombinant, human SGK3 amino acids 119-end
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, human SGK3 amino acids 119-end, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
      Entrez Gene Number
      Entrez Gene SummaryThis gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
      Gene Symbol
      • SGK3
      • SGK2
      • CISK
      • DKFZp781N0293
      • SGKL
      Protein TargetSGK3
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q96BR1 # Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals (By similarity).
      SIZE: 496 amino acids; 57108 Da
      SUBCELLULAR LOCATION: Cytoplasmic vesicle (By similarity). Early endosome (By similarity). Note=Localized in vesicle-like structures and in the early endosome (By similarity).
      TISSUE SPECIFICITY: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle.
      SIMILARITY: SwissProt: Q96BR1 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 PX (phox homology) domain.
      Molecular Weight46.7kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of crosstide KK (12-555)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-647) and in bulk (cat# 14-647-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      14-647M 04053252518300

      Verwandte Produkte & Anwendungen

      Alternative Packsize

      Bestellnummer Beschreibung  
      14-647 SGK3 Protein, active, 10 µg Preis & Verfügbarkeit

      Produktfamilien

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      Kategorien

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases