MMA130 MilliporeMillicell® µ-Angiogenesis Activation Assay Kit
The Millicell μ-Angiogenesis activation assay kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution.
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Übersicht
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Key Spec Table
Key Applications | Detection Methods |
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ACT, CULT | Fluorescent |
Description | |
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Catalogue Number | MMA130 |
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Description | Millicell® µ-Angiogenesis Activation Assay Kit |
Overview | Overview Studying how compounds affect angiogenesis, either to promote or inhibit new capillary tube formation can lead to therapies affecting wound healing, tissue regeneration, cardiovascular disease, stroke, tumor progression, and more. The Millicell μ-Angiogenesis activation and inhibition kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution. Benefits
Studying how compounds affect angiogenesis, either to promote or inhibit new capillary tube formation, can lead to therapies affecting wound healing, tissue regeneration, cardiovascular disease, stroke, tumor progression, and more. The Millicell® μ-Angiogenesis activation and inhibition assay kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution. Applications
For more information on Cell Culture & Systems visit: www.emdmillipore.com/cellculture |
Materials Required but Not Delivered | 1. Inverted Light Microscope 2. Fluorescent microscope (if Calcein AM is used) 3. Precision pipettes 4. Accutase™ Cell Dissociation Solution (Catalog. No. SCR005) 5. Human umbilical vein endothelial cells (HUVEC) (Catalog No. SCCE001) or any other experimental cell lines capable of tube formation. 6. EndoGRO™ LS Complete Medium (Cat. No. SCME001) or other endothelial cell basal medium. 7. Phosphate-Buffered Saline (1X PBS) (Catalog No. BSS-1005-B) 8. Sterile distilled water (Cat. No. TMS-006-C or TMS-006-B) 9. Low speed centrifuge 10. Sterile eppendorf tubes 11. Precision pipette tips. We recommend 0.1–10 mL TipOne filter tips (USA Scientific Catalog No. 1121-3810) or Rainin’s 20 µL Precision Pipette Tips (Rainin Catalog No. RT-L10S) 12. 37ºC Incubator with 5% CO2 13. Hemacytometer 14. Trypan Blue 15. DMSO |
Background Information | Angiogenesis, the formation of new blood vessels from a pre-existing vascular network, occurs normally in development and is critical for a majority of the vessel formation that occurs during embryogenesis, tissue generation, and wound healing. However, abnormal blood vessel growth, either excessive or insufficient, can be the underlying cause of many deadly and debilitating diseases including cancer, cardiovascular disease, stroke, and diabetic and age-related blindness. Identification of specific compounds that promote or inhibit angiogenesis may provide promising treatments for these diseases. Tubular formation is a multi-step process involving cell adhesion, migration, differentiation, and growth. Millipore’s Millicell® µ-Angiogenesis Inhibition Assay provides an efficient system for the rapid and accurate identification of factors that inhibit tube formation of endothelial cells. The µ-Angiogenesis slide, with enhanced optical capabilities in a microscale format, allows for real time and continuous monitoring of tube formation in a simplifed and reproducible manner. |
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Material Size | 1 Kit |
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Bestellnummer | GTIN |
MMA130 | 04053252005282 |
Documentation
Broschüre
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EpiGRO™, EndoGRO™ and FibroGRO™ Reagents |
Posters
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Poster: Tumor Metastasis |
Gebrauchsanleitungen
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Millicell-Angiogenesis Activation Assay |