445888 Sigma-AldrichMetastin (45-54) - Calbiochem
Metastin (45-54), CAS 374675-21-5, is a decapeptide that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors).
More>> Metastin (45-54), CAS 374675-21-5, is a decapeptide that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors). Less<<Metastin (45-54) - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: KiSS-1 (112-121), Kisspeptin-10, H-YNWNSFGLRF-NH₂
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Übersicht
| Replacement Information |
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Key Spec Table
| Empirical Formula |
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| C₆₃H₈₃N₁₇O₁₄ |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 445888-1MG |
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Kst.-Ampulle | 1 mg |
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| Description | |
|---|---|
| Overview | A decapeptide with C-terminally amidated LRF-motif that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors). Induces an increase in intracellular Ca2+ levels in CHO/h175 and CHO/AXOR12:Gqi5 cells and exhibits about 8-fold higher receptor binding affinity (Ki = 42 pM) compared to Metastin (Cat. No. 445885). |
| Catalogue Number | 445888 |
| Brand Family | Calbiochem® |
| Synonyms | KiSS-1 (112-121), Kisspeptin-10, H-YNWNSFGLRF-NH₂ |
| References | |
|---|---|
| References | Kotani, M., et al. 2001. J. Biol. Chem. 276, 34631. Ohtaki, T., et al. 2001. Nature 411, 613. Muir, A.I., et al. 2001. J. Biol. Chem. 276, 28969. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White lyophilized solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₆₃H₈₃N₁₇O₁₄ |
| Chemical formula | C₆₃H₈₃N₁₇O₁₄ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Metastin (45-54), CAS 374675-21-5, is a decapeptide that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors). |
| Biological Information | |
|---|---|
| Primary Target | AXOR12 and hOT7T175 |
| Primary Target K<sub>i</sub> | 42 pM for AXOR12 and hOT7T175 |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Bestellnummer | GTIN |
| 445888-1MG | 04055977204636 |
Documentation
Metastin (45-54) - Calbiochem SDB
| Titel |
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Metastin (45-54) - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
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| 445888 |
Literatur
| Übersicht |
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| Kotani, M., et al. 2001. J. Biol. Chem. 276, 34631. Ohtaki, T., et al. 2001. Nature 411, 613. Muir, A.I., et al. 2001. J. Biol. Chem. 276, 28969. |