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CC065 Human Tenascin-C Purified Protein

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CC065
100 µg  
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      Übersicht

      Key Spec Table

      Key Applications
      PC, CULT
      Description
      Catalogue NumberCC065
      ReplacesCC066
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionHuman Tenascin-C Purified Protein
      OverviewPurified Human Tenascin-C Protien. Tenascin is known to: 1) play an active role in development of central nervous system and mesenchymal-derived organs; 2) exist in vasculature of tumors in adults; and 3) function in cell adhesion. By SDS-PAGE analysis, the protein migrates around 280-300kD.
      Alternate Names
      • TN-C
      • Tenascin
      • Hexabrachion
      • Cytotactin
      • Neuronectin
      Product Information
      PresentationPurified protein supplied as a liquid in PBS containing no preservatives.
      Quality LevelMQ100
      Applications
      Key Applications
      • Positive Control
      • Cell Culture
      Application NotesCell adhesion assays.

      Optimal working dilutions must be determined by end user.
      Biological Information
      Concentration0.1 mg/mL
      Purity> 97% pure by SDS-PAGE
      SourceHuman glioma cell line (U251).
      Entrez Gene Number
      Gene Symbol
      • TNC
      • Hexabrachion
      • HXB
      • GMEM
      • TN
      • Neuronectin
      • Tenascin-C
      • MGC167029
      • JI
      • TN-C
      • Cytotactin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
      SIZE: 2201 amino acids; 240866 Da
      SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
      SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
      PTM: N-glycosylated (By similarity).
      SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.
      Stem Cell Type
      • Human Embryonic Stem Cells
      • Mesenchymal Stem Cells
      • Neural Stem Cells
      • Hematopoietic Stem Cells
      • Epithelial Cells
      • Pancreatic Stem Cells
      • Induced Pluripotent Stem Cells
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70ºC for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Bestellnummer GTIN
      CC065 04053252671982