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ABN192 Anti-ZFP36L1 Antibody

Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.

Anti-ZFP36L1 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: ZFP36L1, BERG36, BRF1, ERF1, RNF162B, TIS11B UniProt Number: Q07352
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ABN192
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, B, Eq, CaWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN192
      DescriptionAnti-ZFP36L1 Antibody
      Alternate Names
      • Zinc finger protein 36, C3H1 type-like 1
      • Butyrate response factor 1
      • EGF-response factor 1
      • ERF-1
      • Protein TIS11B
      Background InformationAs a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.
      References
      Product Information
      FormatAffinity Purified
      Control
      • HeLa cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of ZFP36L1.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Bovine
      • Horse
      • Canine
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Horse, and Canine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ZFP36L1
      • BERG36
      • BRF1
      • ERF1
      • RNF162B
      • TIS11B
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~38 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HeLa cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABN192 04053252826023

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      Kategorien

      Life Science Research > Antibodies and Assays > Primary Antibodies