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ABT41 Anti-Myosin XIX (Myo19) Antibody

Anti-Myosin XIX (Myo19) Antibody detects level of Myosin XIX (Myo19) & has been published & validated for use in IH(P).

Anti-Myosin XIX (Myo19) Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: MYO19, MYOHD1 UniProt Number: Q96H55
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ABT41
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, CaIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT41
      DescriptionAnti-Myosin XIX (Myo19) Antibody
      Alternate Names
      • Myosin-XIX
      • Myosin head domain-containing protein 1
      Background InformationMyosin XIX (Myo19) is the founding member of a novel class of myosin that associates with mitochondria. Both endogenous Myo19 and GFP-Myo19 exihibit localization to mitochondria. Myosins are actin-based motor molecules with ATPase activity. Myo19 is involved in actin-based mitochondrial motility. Myo19 mRNA is expressed in multiple tissues, and antibodies to human Myo19 detect an approximately 109 kDa band in multiple cell lines.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human cardiac muscle tissue
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Myosin XIX (Myo19) Antibody detects level of Myosin XIX (Myo19) & has been published & validated for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Myosin XIX (Myo19).
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Canine
      Species Reactivity NoteDemonstrated to react with Human.
      Predicted to react with Canine based on 100% sequence homology. Other homologies: Rat and Mouse (92% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MYO19
      • MYOHD1
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility.

      SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton. Mitochondrion outer membrane. Note: Probably associated with the outer membrane via its N-terminal mitochondrial targeting region. TISSUE SPECIFICITY: Widely expressed in multiple tissues and cell lines.

      SEQUENCE SIMILARITIES: Contains 2 IQ domains.

      Contains 1 myosin head-like domain.

      SEQUENCE CAUTION: The sequence BAD92272.1 differs from that shown. Reason: Erroneous initiation.
      Molecular Weight109 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human cardiac muscle tissue.

      Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Myosin XIX (Myo19) in human cardiac muscle tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABT41 04053252420627