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ABT316 Anti-LTBP-3 Antibody

This Anti-LTBP-3 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of LTBP-3.

Anti-LTBP-3 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: LTBP3 UniProt Number: Q9NS15
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ABT316
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT316
      DescriptionAnti-LTBP-3 Antibody
      Alternate Names
      • Latent-transforming growth factor beta-binding protein 3
      • LTBP-3
      Background InformationLTBP3 is a critical secreted protein that is part of the multi-protein complex that controls the action and release of the powerful developmental, immune, and signaling factor TGF-beta. LTBP3’s specific role appears to be in regulating the activation of the TGFB1 precursor complex. The removal of LTBP3 is essential for the activation of the complex. LTBP3 is expressed in many tissues including heart, skeletal muscle, prostate, testis, small intestine, ovary, pancreas, and liver. Recent research also demonstrates that LTBP3 plays important roles in many human carcinomas including breast, hepatic, and mesothelioma.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-LTBP-3 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of LTBP-3.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 2.0 µg/mL from a representative lot detected LTBP-3 in 10 µg of U2OS conditioned media.
      Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LTBP-3 in human prostate tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human LTBP-3.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LTBP3
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~240 kDa observed. The calculated molecular weight of this protein is 139 kDa, but can be observed at ~240 kDa due to high glycosylation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse testis tissue lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected LTBP-3 in 10 µg of mouse testis tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABT316 04055977039498