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ABE335 Anti-FOXL2 Antibody

This Anti-FOXL2 Antibody is validated for use in Western Blotting for the detection of FOXL2.

Anti-FOXL2 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: FOXL2 UniProt Number: P58012
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ABE335
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE335
      DescriptionAnti-FOXL2 Antibody
      Alternate Names
      • Forkhead box protein L2
      Background InformationForkhead box protein L2 (FOXL2) is a fork-head transcription factor that is expressed in developing gonad and in granulosa cells of the mature ovary. It plays a role in repressing the development of testis, and facilitating the differentiation and maintenance of the ovary. Mutations in the FOXL2 gene result in blepharophimosis ptosis epicanthus inversus (BPES) syndrome, which is characterized by craniofacial defects and premature ovarian failure. FOXL2 has also been implicated in the development of ovarian granulosa cell tumors.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human pituitary
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-FOXL2 Antibody is validated for use in Western Blotting for the detection of FOXL2.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human FOXL2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse, Bovine, Porcine, and Rabbit based on 100% sequence homology. Other homologies: Chicken (77% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FOXL2
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~50 kDa observed. An uncharacterized band may appear at ~25 kDa in some lysates. The calculated molecular weight is 39 kDa, however FOXL2 has been shown as a ~50 kDa band in western blots (Marongiu, M., et al. (2010). PLOS One. 5(3):1-9).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human pituitary tissue lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected FOXL2 in 10 µg of human pituitary tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABE335 04053252551796

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      Kategorien

      Life Science Research > Antibodies and Assays > Primary Antibodies