Millipore Sigma Vibrant Logo

203694 bpV(bipy) - Calbiochem

A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation).

bpV(bipy) - Calbiochem: Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.

Sinônimos: Potassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV

Primary Target: phosphotyrosine phosphatase
View Products on Sigmaaldrich.com
203694
Ver preços e disponibilidade

Panorama geral

Replacement Information

Tabela com principais espec.

Empirical Formula
K[VO(O₂)₂C₁₀H₈N₂] · 3H₂O

Preço e Disponibilidade

Número de catálogo DisponibilidadeEmbalagem Qtde/Emb. Preço Quantidade
203694-5MG
Verificando a disponibilidade...
—
Disponibilidade limitada Disponibilidade limitada
Insira quantidade 
Descontinuado
Quantidades limitadas disponíveis
Disponibilidade a ser confirmada
    Restante: será informado
      Restante: será informado
      Vai informar
      Contatar o serviço de atendimento ao cliente
      Contact Customer Service

      		 Ampola plástica 5 mg
      Recuperando preço...
      O preço não pôde ser recuperado
      Quantidade mínima necessária para ser múltipla de
      Maximum Quantity is
      Após finalização do pedido Mais informações
      Você salvou ()
       
      —
      Solicitar preço
      		 —
      Description
      OverviewA potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM).
      Catalogue Number203694
      Brand Family Calbiochem®
      SynonymsPotassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV
      References
      ReferencesSchmid, A.C., et al. 2004. FEBS Lett. 566, 35.
      Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.
      Product Information
      ATP CompetitiveN
      FormYellow to orange solid
      Hill FormulaK[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
      Chemical formulaK[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetphosphotyrosine phosphatase
      Primary Target IC<sub>50</sub>18 nM against PTEN
      Primary Target K<sub>i</sub>100 nM for phosphotyrosine phosphatase
      Purity≥95% by ⁵¹V-NMR
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      203694-5MG 04055977204414

      Documentation

      bpV(bipy) - Calbiochem MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      bpV(bipy) - Calbiochem Certificados de análise

      TítuloNúmero do lote
      203694

      Referências

      Visão geral de referência
      Schmid, A.C., et al. 2004. FEBS Lett. 566, 35.
      Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.

      Brochura

      Título
      Protein Phosphatases Technical Bulletin
      Ficha de dados

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-May-2008 RFH
      SynonymsPotassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV
      DescriptionA potent inhibitor of phosphotyrosine phosphatase activity (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM).
      FormYellow to orange solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaK[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
      Structure formulaStructure formula
      Purity≥95% by ⁵¹V-NMR
      SolubilityH₂O (5 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Harmful
      ReferencesSchmid, A.C., et al. 2004. FEBS Lett. 566, 35.
      Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.