516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
More>> Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Less<<Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.
Sinônimos: Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
Produtos recomendados
Panorama geral
| Replacement Information |
|---|
Tabela com principais espec.
| CAS # | Empirical Formula |
|---|---|
| 26305-03-3 | C₃₄H₆₃N₅O₉ |
Preço e Disponibilidade
| Número de catálogo | Disponibilidade | Embalagem | Qtde/Emb. | Preço | Quantidade | |
|---|---|---|---|---|---|---|
| 516481-25MG |
|
Ampola plástica | 25 mg |
|
— | |
| 516481-5MG |
|
Ampola plástica | 5 mg |
|
— |
| Description | |
|---|---|
| Overview | A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437). |
| Effective concentration: 1.0 µM. | |
| Catalogue Number | 516481 |
| Brand Family | Calbiochem® |
| Synonyms | Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid |
| Product Information | |
|---|---|
| CAS number | 26305-03-3 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₃₄H₆₃N₅O₉ |
| Chemical formula | C₃₄H₆₃N₅O₉ |
| Optical rotation | Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C). |
| Reversible | Y |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Primary Target | cathepsin D |
| Primary Target IC<sub>50</sub> | EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS | |
|---|---|
| RTECS | SC6155000 |
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information |
|---|
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Número de catálogo | GTIN |
| 516481-25MG | 07790788055837 |
| 516481-5MG | 04055977198836 |
Documentation
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem MSDS
| Título |
|---|
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem Certificados de análise
| Título | Número do lote |
|---|---|
| 516481 |
Referências
| Visão geral de referência |
|---|
| Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259. |
Brochura
| Título |
|---|
| Western Blotting Tools |
Informações técnicas
| Título |
|---|
| Protein Blotting Handbook: 6th Edition |