Pellicon® Mini Cassette Holder
Simple design makes process development and small scale pharmaceutical manufacturing simple and efficient.
The Pellicon® Mini holder operates one to three Pellicon® 2 Mini cassettes in parallel for total areas of 0.1 to 0.3 m2 (1.1 – 3.3 ft2) or Pellicon® 3 cassettes (88 cm2 and 0.11 m2) for a total area of 88 cm2 to 0.55 m2. This sanitary holder is tightened with a small torque wrench to compress the cassettes between a manifold plate that conveys fluids in and out of the cassettes and an end plate that seals the cassettes together.
The Mini holder is designed for process development and small volume pharmaceutical manufacturing.
The Pellicon® Mini holder operates one to three Pellicon® 2 Mini cassettes in parallel for total areas of 0.1 to 0.3 m2 (1.1 – 3.3 ft2) or Pellicon® 3 cassettes (88 cm2 and 0.11 m2) for a total area of 88 cm2 to 0.55 m2. This sanitary holder is tightened with a small torque wrench to compress the cassettes between a manifold plate that conveys fluids in and out of the cassettes and an end plate that seals the cassettes together.
The Mini holder is designed for process development and small volume pharmaceutical manufacturing. Less<<
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FAQ
| Pergunta | Resposta |
|---|---|
| What is the minimum working volume for the Pellicon II Mini system? | Depending on the length of tubing, and the set up of the system, it is possible to get down to a working volume of 100 mL with the Pellicon II Mini System. |
| When a Pellicon Holder is ordered, what do I receive? | The holders are supplied with a socket wrench, 3/4" sanitary clamp adapters, clamps, and gaskets. The pressure gauges need to be ordered separately by ordering catalog number XX4200075. Only one 0- 100 psi analog gauge is supplied with this number, and it is recommended to operate with two gauges, one for the feed and one for the retentate. Conversely, order the appropriate Pellicon fitting kit which contains the pressure gauges, fittings, clamps, and valves for connecting the pump to the holder.
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| What parts do I need in order to operate the Pellicon II Mini system? | In addition to the holder (catalog number XX42PMINI) and cassettes (catalog number P2.......), it is recommended to purchase the fitting kit (catalog number XX42PFK01) which contains all tees, clamps, gaskets, and retentate valve, and to purchase 2 gauges (one for the feed and one for the retentate). The gauges may be either the analog pressure gauges (catalog number B26524, 0- 60 psig, one gauge per pack) or digital pressure gauges (catalog number XX42PSG01, 0-100 psig, 2 gauges per pack). Also be sure to choose a pump and appropriate tubing to meet your process needs. Contact Technical Service for assistance. |
| What is the sample volume range for the Pellicon II Mini system? | The Pellicon II Mini system is capable of volumes in the approximate range of 1- 50 L concentrating down to 100 mL. More or less volume can be processed depending on the individual needs of the operation, ie. process time, sensitivity of product, etc. |
| What are turbulence promoters? | Turbulence promoters are screens that are inserted into the feed and/or filtrate channels in TFF modules in order to increase the "turbulence" in the channels of the module and to reduce the occurence of concentration polarization (the gel layer that can form on membranes therefore slowing flux). These turbulence promoted channels allow for higher fluxes with lower pumping requirements which makes them more efficient than open channels without turbulence promoters. |
| What is the hold up volume of a Pellicon 2 mini holder? | The hold-up volume for the Pellicon 2 mini-holder, catalogue number XX42PMINI, is 5.3 ml on the feed/retentate side and 6.4 ml on the permeate side. |
| What are important spare parts for the Mini Pellicon holder? | 1. Washer and Bronze nuts - catalogue number XX42MT073 2. Tie rod - catalogue number 17813X1 3. Tie rod spacers - Catalogue number 27099X1 |
| Can the Pellicon II Mini Holder be autoclaved? | The Pellicon II Mini holder without membrane cassettes may be autoclaved. The holder is constructed of stainless steel and thermoplastic rubber feet. |
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