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516566 PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem

The PPARγ Antagonist III, G3335, also referenced under CAS 36099-95-3, controls the biological activity of PPARγ.

Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.

Sinônimos: H-Trp-Glu-OH

Primary Target: PPARγ
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CAS #Empirical Formula
36099-95-3C₁₆H₁₉N₃O₅

Preço e Disponibilidade

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516566-50MG
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      Description
      OverviewA cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD = ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
      Catalogue Number516566
      Brand Family Calbiochem®
      SynonymsH-Trp-Glu-OH
      References
      ReferencesYe, F., et al. 2006. Chembiochem 7, 74.
      Product Information
      CAS number36099-95-3
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₆H₁₉N₃O₅
      Chemical formulaC₁₆H₁₉N₃O₅
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPPARγ
      Primary Target IC<sub>50</sub>kd = ~ 8 µM as PPARγ antagonist
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de catálogo GTIN
      516566-50MG 04055977198195

      Documentation

      PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem MSDS

      Título

      Ficha de Segurança de Produtos (MSDS) 

      PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem Certificados de análise

      TítuloNúmero do lote
      516566

      Referências

      Visão geral de referência
      Ye, F., et al. 2006. Chembiochem 7, 74.
      Ficha de dados

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-August-2024 JSW
      SynonymsH-Trp-Glu-OH
      DescriptionA cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number36099-95-3
      Chemical formulaC₁₆H₁₉N₃O₅
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityH₂O (30 mg/ml). Addition of a small amount of acid or base may be required for complete solubilization.
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesYe, F., et al. 2006. Chembiochem 7, 74.